Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab Protocol
Primary renal lymphoma (PRL) is a rare disease of which the etiology and pathogenesis remain controversial, and there is currently no standard treatment for it. We present the results of a long-term followup of two patients who were diagnosed with PRL and treated with cyclophosphamide, adriamycin,...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/726424 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849468993913487360 |
|---|---|
| author | F. Vázquez-Alonso I. Puche-Sanz C. Sánchez-Ramos J. Flores-Martín J. Vicente-Prados J. M. Cózar-Olmo |
| author_facet | F. Vázquez-Alonso I. Puche-Sanz C. Sánchez-Ramos J. Flores-Martín J. Vicente-Prados J. M. Cózar-Olmo |
| author_sort | F. Vázquez-Alonso |
| collection | DOAJ |
| description | Primary renal lymphoma (PRL) is a rare disease of which the etiology and pathogenesis remain controversial, and there is currently no standard treatment for it. We present the results of a long-term followup of two patients who were diagnosed with PRL and treated with cyclophosphamide, adriamycin, vincristine, prednisolone and rituximab (CHOP + R) regimen. Both patients reached a complete response, and there is no evidence of recurrence after 4.5- and 5-year followup periods. Based on our experience and other recently published studies, we recommend the combination of CHOP + rituximab as the elective treatment for this disease. To our knowledge, this is the longest followup period with a complete response that has been reported with this modality of treatment. |
| format | Article |
| id | doaj-art-fece371ae80e470eaf06e33d30e40402 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-fece371ae80e470eaf06e33d30e404022025-08-20T03:25:40ZengWileyCase Reports in Oncological Medicine2090-67062090-67142012-01-01201210.1155/2012/726424726424Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab ProtocolF. Vázquez-Alonso0I. Puche-Sanz1C. Sánchez-Ramos2J. Flores-Martín3J. Vicente-Prados4J. M. Cózar-Olmo5Department of Urology, Hospital Universitario Virgen de las Nieves, 18014 Granada, SpainDepartment of Urology, Hospital Universitario Virgen de las Nieves, 18014 Granada, SpainDepartment of Hematology, Hospital Universitario Virgen de las Nieves, 18014 Granada, SpainDepartment of Urology, Hospital Universitario Virgen de las Nieves, 18014 Granada, SpainDepartment of Urology, Hospital Universitario Virgen de las Nieves, 18014 Granada, SpainDepartment of Urology, Hospital Universitario Virgen de las Nieves, 18014 Granada, SpainPrimary renal lymphoma (PRL) is a rare disease of which the etiology and pathogenesis remain controversial, and there is currently no standard treatment for it. We present the results of a long-term followup of two patients who were diagnosed with PRL and treated with cyclophosphamide, adriamycin, vincristine, prednisolone and rituximab (CHOP + R) regimen. Both patients reached a complete response, and there is no evidence of recurrence after 4.5- and 5-year followup periods. Based on our experience and other recently published studies, we recommend the combination of CHOP + rituximab as the elective treatment for this disease. To our knowledge, this is the longest followup period with a complete response that has been reported with this modality of treatment.http://dx.doi.org/10.1155/2012/726424 |
| spellingShingle | F. Vázquez-Alonso I. Puche-Sanz C. Sánchez-Ramos J. Flores-Martín J. Vicente-Prados J. M. Cózar-Olmo Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab Protocol Case Reports in Oncological Medicine |
| title | Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab Protocol |
| title_full | Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab Protocol |
| title_fullStr | Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab Protocol |
| title_full_unstemmed | Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab Protocol |
| title_short | Primary Renal Lymphoma: Long-Term Results of Two Patients Treated with a Chemotherapy + Rituximab Protocol |
| title_sort | primary renal lymphoma long term results of two patients treated with a chemotherapy rituximab protocol |
| url | http://dx.doi.org/10.1155/2012/726424 |
| work_keys_str_mv | AT fvazquezalonso primaryrenallymphomalongtermresultsoftwopatientstreatedwithachemotherapyrituximabprotocol AT ipuchesanz primaryrenallymphomalongtermresultsoftwopatientstreatedwithachemotherapyrituximabprotocol AT csanchezramos primaryrenallymphomalongtermresultsoftwopatientstreatedwithachemotherapyrituximabprotocol AT jfloresmartin primaryrenallymphomalongtermresultsoftwopatientstreatedwithachemotherapyrituximabprotocol AT jvicenteprados primaryrenallymphomalongtermresultsoftwopatientstreatedwithachemotherapyrituximabprotocol AT jmcozarolmo primaryrenallymphomalongtermresultsoftwopatientstreatedwithachemotherapyrituximabprotocol |