Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans.

Proteasome inhibition triggers tissue-specific immune responses against different pathogens in C. elegans.

Protein quality control pathways play important roles in resistance against pathogen infection. For example, the conserved transcription factor SKN-1/NRF up-regulates proteostasis capacity after blockade of the proteasome and also promotes resistance against bacterial infection in the nematode Caeno...

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Main Authors: Manish Grover, Spencer S Gang, Emily R Troemel, Michalis Barkoulas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-03-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002543&type=printable
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