A normal genetic variation modulates synaptic MMP‐9 protein levels and the severity of schizophrenia symptoms
Abstract Matrix metalloproteinase 9 (MMP‐9) has recently emerged as a molecule that contributes to pathological synaptic plasticity in schizophrenia, but explanation of the underlying mechanisms has been missing. In the present study, we performed a phenotype‐based genetic association study (PGAS) i...
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| Main Authors: | Katarzyna Lepeta, Katarzyna J Purzycka, Katarzyna Pachulska‐Wieczorek, Marina Mitjans, Martin Begemann, Behnam Vafadari, Krystian Bijata, Ryszard W Adamiak, Hannelore Ehrenreich, Magdalena Dziembowska, Leszek Kaczmarek |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2017-06-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201707723 |
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