Renal replacement therapy after liver transplantation
Objective: to analyze the causes of acute renal failure (ARF) and to study the efficiency of renal replacement therapy (RRT) in the treatment of this condition after liver transplantation.Materials and methods. Eighty liver transplantations made at the N.V. Sklifosovsky Research Institute of Emergen...
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| Format: | Article |
| Language: | English |
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2018-08-01
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| Series: | Трансплантология (Москва) |
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| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/241 |
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| author | S. V. Zhuravel Ye. N. Dorofeyeva N. K. Kuznetsova A. O. Chugunov V. V. Kiselev A. M. Talyzin L. V. Donova A. V. Chzhao |
| author_facet | S. V. Zhuravel Ye. N. Dorofeyeva N. K. Kuznetsova A. O. Chugunov V. V. Kiselev A. M. Talyzin L. V. Donova A. V. Chzhao |
| author_sort | S. V. Zhuravel |
| collection | DOAJ |
| description | Objective: to analyze the causes of acute renal failure (ARF) and to study the efficiency of renal replacement therapy (RRT) in the treatment of this condition after liver transplantation.Materials and methods. Eighty liver transplantations made at the N.V. Sklifosovsky Research Institute of Emergency Care from 2000 to 2008 were analyzed. The patients were divided into 2 groups: 1) 29 patients with evolving ARF who received RRT in the postoperative period; 2) 51 patients who had no indications for RRT.Results. Postoperative RRT was performed in 29 (36.3%) patients. Of them, 23 patients had been identified to have the hepatorenal syndrome in the preoperative period. Renal function recovered in 20 (72.4%) of the 29 patients who needed RRT during the performed treatment and they were discharged from the clinic. Due to the conducted treatment, these patients showed stabilization and their ARF resolution occurred within 12.7±6.2 days. The mean number of performed sessions required to restore renal function was 8.8 (range 1 to 56).Conclusion. Preoperative hepatorenal syndrome is a predictor of ARF in the postoperative period. At the same time ARD has a good prognosis after liver transplantation. With a primary non-functioning graft, extracorporeal techniques are ineffective and maintenance therapy used prior to liver retransplantation. |
| format | Article |
| id | doaj-art-feaaa95b103746579a6f42c47daa9617 |
| institution | Kabale University |
| issn | 2074-0506 2542-0909 |
| language | English |
| publishDate | 2018-08-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj-art-feaaa95b103746579a6f42c47daa96172025-08-20T03:35:07ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-08-0101495210.23873/2074-0506-2009-0-1-49-52230Renal replacement therapy after liver transplantationS. V. Zhuravel0Ye. N. Dorofeyeva1N. K. Kuznetsova2A. O. Chugunov3V. V. Kiselev4A. M. Talyzin5L. V. Donova6A. V. Chzhao7Liver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareLiver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareLiver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareLiver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareLiver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareLiver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareLiver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareLiver Transplantation Center, N.V. Sklifosovsky Research Institute of Emergency CareObjective: to analyze the causes of acute renal failure (ARF) and to study the efficiency of renal replacement therapy (RRT) in the treatment of this condition after liver transplantation.Materials and methods. Eighty liver transplantations made at the N.V. Sklifosovsky Research Institute of Emergency Care from 2000 to 2008 were analyzed. The patients were divided into 2 groups: 1) 29 patients with evolving ARF who received RRT in the postoperative period; 2) 51 patients who had no indications for RRT.Results. Postoperative RRT was performed in 29 (36.3%) patients. Of them, 23 patients had been identified to have the hepatorenal syndrome in the preoperative period. Renal function recovered in 20 (72.4%) of the 29 patients who needed RRT during the performed treatment and they were discharged from the clinic. Due to the conducted treatment, these patients showed stabilization and their ARF resolution occurred within 12.7±6.2 days. The mean number of performed sessions required to restore renal function was 8.8 (range 1 to 56).Conclusion. Preoperative hepatorenal syndrome is a predictor of ARF in the postoperative period. At the same time ARD has a good prognosis after liver transplantation. With a primary non-functioning graft, extracorporeal techniques are ineffective and maintenance therapy used prior to liver retransplantation.https://www.jtransplantologiya.ru/jour/article/view/241orthotopic liver transplantationacute renal failurehepatorenal syndromerenal replacement therapy |
| spellingShingle | S. V. Zhuravel Ye. N. Dorofeyeva N. K. Kuznetsova A. O. Chugunov V. V. Kiselev A. M. Talyzin L. V. Donova A. V. Chzhao Renal replacement therapy after liver transplantation Трансплантология (Москва) orthotopic liver transplantation acute renal failure hepatorenal syndrome renal replacement therapy |
| title | Renal replacement therapy after liver transplantation |
| title_full | Renal replacement therapy after liver transplantation |
| title_fullStr | Renal replacement therapy after liver transplantation |
| title_full_unstemmed | Renal replacement therapy after liver transplantation |
| title_short | Renal replacement therapy after liver transplantation |
| title_sort | renal replacement therapy after liver transplantation |
| topic | orthotopic liver transplantation acute renal failure hepatorenal syndrome renal replacement therapy |
| url | https://www.jtransplantologiya.ru/jour/article/view/241 |
| work_keys_str_mv | AT svzhuravel renalreplacementtherapyafterlivertransplantation AT yendorofeyeva renalreplacementtherapyafterlivertransplantation AT nkkuznetsova renalreplacementtherapyafterlivertransplantation AT aochugunov renalreplacementtherapyafterlivertransplantation AT vvkiselev renalreplacementtherapyafterlivertransplantation AT amtalyzin renalreplacementtherapyafterlivertransplantation AT lvdonova renalreplacementtherapyafterlivertransplantation AT avchzhao renalreplacementtherapyafterlivertransplantation |