POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSIS
Aim. To estimate whether CYP1A1, CYP1A2, CYP19, SULT1A1 gene polymorphisms are associated with genital endometriosis in infertile women. Materials and Methods. We evaluated allele frequencies of aforementioned gene polymorphisms in 100 consecutive women with genital endometriosis-associated infertil...
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Kemerovo State Medical University
2018-09-01
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| Series: | Фундаментальная и клиническая медицина |
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| Online Access: | https://fcm.kemsmu.ru/jour/article/view/100 |
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| author | LARISA N. Danilova VITALIY O. Chervov NATALIA V. Artymuk LYUDMILA A. Gordeeva |
| author_facet | LARISA N. Danilova VITALIY O. Chervov NATALIA V. Artymuk LYUDMILA A. Gordeeva |
| author_sort | LARISA N. Danilova |
| collection | DOAJ |
| description | Aim. To estimate whether CYP1A1, CYP1A2, CYP19, SULT1A1 gene polymorphisms are associated with genital endometriosis in infertile women. Materials and Methods. We evaluated allele frequencies of aforementioned gene polymorphisms in 100 consecutive women with genital endometriosis-associated infertility and 100 women with tubal infertility utilizing polymerase chain reaction-restriction fragment length polymorphism. Results. We did not find any statistically significant associations between the polymorphisms within the CYP1A1, CYP1A2, CYP19, SULT1A1 genes and genital endometriosis in infertile patients. Conclusions. Further studies are needed to explore the genetic risk factors associated with endometriosis-associated infertility. |
| format | Article |
| id | doaj-art-fea2c796823b435e8072d3d8b6faaf2e |
| institution | Kabale University |
| issn | 2500-0764 2542-0941 |
| language | Russian |
| publishDate | 2018-09-01 |
| publisher | Kemerovo State Medical University |
| record_format | Article |
| series | Фундаментальная и клиническая медицина |
| spelling | doaj-art-fea2c796823b435e8072d3d8b6faaf2e2025-08-20T03:42:38ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412018-09-0133253499POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSISLARISA N. Danilova0VITALIY O. Chervov1NATALIA V. Artymuk2LYUDMILA A. Gordeeva3Reshetova Kemerovo Regional Clinical Perinatal CenterKemerovo State Medical UniversityKemerovo State Medical UniversityInstitute of Human Ecology of the Siberian Branch of the Russian Academy of SciencesAim. To estimate whether CYP1A1, CYP1A2, CYP19, SULT1A1 gene polymorphisms are associated with genital endometriosis in infertile women. Materials and Methods. We evaluated allele frequencies of aforementioned gene polymorphisms in 100 consecutive women with genital endometriosis-associated infertility and 100 women with tubal infertility utilizing polymerase chain reaction-restriction fragment length polymorphism. Results. We did not find any statistically significant associations between the polymorphisms within the CYP1A1, CYP1A2, CYP19, SULT1A1 genes and genital endometriosis in infertile patients. Conclusions. Further studies are needed to explore the genetic risk factors associated with endometriosis-associated infertility.https://fcm.kemsmu.ru/jour/article/view/100эндометриозбесплодиеполиморфизмcyp1a1cyp1a2cyp19sult1aendometriosisinfertilitygene polymorphismscyp1a1cyp1a2cyp19sult1a |
| spellingShingle | LARISA N. Danilova VITALIY O. Chervov NATALIA V. Artymuk LYUDMILA A. Gordeeva POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSIS Фундаментальная и клиническая медицина эндометриоз бесплодие полиморфизм cyp1a1 cyp1a2 cyp19 sult1a endometriosis infertility gene polymorphisms cyp1a1 cyp1a2 cyp19 sult1a |
| title | POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSIS |
| title_full | POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSIS |
| title_fullStr | POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSIS |
| title_full_unstemmed | POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSIS |
| title_short | POLYMORPHISMS OF THE CYP1A1, CYP1A2, CYP19, AND SULT1A1 GENES ARE NOT ASSOCIATED WITH INFERTILITY IN WOMEN WITH GENITAL ENDOMETRIOSIS |
| title_sort | polymorphisms of the cyp1a1 cyp1a2 cyp19 and sult1a1 genes are not associated with infertility in women with genital endometriosis |
| topic | эндометриоз бесплодие полиморфизм cyp1a1 cyp1a2 cyp19 sult1a endometriosis infertility gene polymorphisms cyp1a1 cyp1a2 cyp19 sult1a |
| url | https://fcm.kemsmu.ru/jour/article/view/100 |
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