HOXD1 regulates neural crest cells differentiation and polycerate development in sheep

HOXD1 regulates neural crest cells differentiation and polycerate development in sheep

Abstract The polycerate trait in sheep is a complex phenotype regulated by polygenes. However, the mechanism behind multi-horned traits development and growth remains unclear. In this study, neural crest cells (NCCs) were isolated from mouse embryos, and the HOXD1 (Homeobox D1) gene was overexpresse...

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Bibliographic Details
Main Authors: Cheng Zhang, Shuhong Zhang, Huifeng Xu, Guan Wang, Huan Zhang, Tenggang Di, Liming Tian, Menghan Chang, Fengyi Gao, Ming Li, Guangli Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Sheep
Polycerate trait
Neural crest cells
HOXD1 gene
Chemokine CXC
Online Access:https://doi.org/10.1038/s41598-025-97865-9
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