Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatment

A high recurrence rate is undesirable after treatment of common bile duct (CBD) stones. A major risk factor identified for recurrence is that invasive techniques, including surgical or endoscopic treatments, will impair the biliary tract system either by direct incision of the CBD or by cutting or d...

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Main Authors: Ye Yang, Zeying Zhao, Shuodong Wu, Dianbo Yao
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Annals of Medicine
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Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2024.2440119
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author Ye Yang
Zeying Zhao
Shuodong Wu
Dianbo Yao
author_facet Ye Yang
Zeying Zhao
Shuodong Wu
Dianbo Yao
author_sort Ye Yang
collection DOAJ
description A high recurrence rate is undesirable after treatment of common bile duct (CBD) stones. A major risk factor identified for recurrence is that invasive techniques, including surgical or endoscopic treatments, will impair the biliary tract system either by direct incision of the CBD or by cutting or dilating the ampulla of Vater. During endoscopic treatment, two main assisted methods for lithotomy, sphincterotomy and papillary balloon dilation, can result in different degrees of damage to the structure and function of the sphincter of Oddi (SO), contributing to slowing of biliary excretion, cholestasis, biliary bacterial infection, and promotion of bile duct stone recurrence. In this review, the relationship between endoscopic lithotomy and structural impairment or functional abnormality of the SO will be summarized, and their relationship with the recurrence of CBD stones will also be analyzed. Further improvement of these endoscopic methods or exploration of some novel methods, such as endoscopic endoclip papilloplasty, temporary insertion of a self-expandable metal stent, and combined application of peroral cholangioscopy, may aid in providing more appropriate treatment for patients with choledocholithiasis, repair or protect the function and structure of SO, reduce or prevent the recurrence of bile duct stones, and improve patient outcomes.
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spelling doaj-art-fe9ba43bbc2f47d2960cb1a2edcc5b352025-08-20T01:56:34ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2024.2440119Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatmentYe Yang0Zeying Zhao1Shuodong Wu2Dianbo Yao3Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, ChinaDepartment of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, ChinaDepartment of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, ChinaDepartment of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, ChinaA high recurrence rate is undesirable after treatment of common bile duct (CBD) stones. A major risk factor identified for recurrence is that invasive techniques, including surgical or endoscopic treatments, will impair the biliary tract system either by direct incision of the CBD or by cutting or dilating the ampulla of Vater. During endoscopic treatment, two main assisted methods for lithotomy, sphincterotomy and papillary balloon dilation, can result in different degrees of damage to the structure and function of the sphincter of Oddi (SO), contributing to slowing of biliary excretion, cholestasis, biliary bacterial infection, and promotion of bile duct stone recurrence. In this review, the relationship between endoscopic lithotomy and structural impairment or functional abnormality of the SO will be summarized, and their relationship with the recurrence of CBD stones will also be analyzed. Further improvement of these endoscopic methods or exploration of some novel methods, such as endoscopic endoclip papilloplasty, temporary insertion of a self-expandable metal stent, and combined application of peroral cholangioscopy, may aid in providing more appropriate treatment for patients with choledocholithiasis, repair or protect the function and structure of SO, reduce or prevent the recurrence of bile duct stones, and improve patient outcomes.https://www.tandfonline.com/doi/10.1080/07853890.2024.2440119Choledocholithiasisendoscopic treatmentsphincter of Oddirecurrence
spellingShingle Ye Yang
Zeying Zhao
Shuodong Wu
Dianbo Yao
Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatment
Annals of Medicine
Choledocholithiasis
endoscopic treatment
sphincter of Oddi
recurrence
title Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatment
title_full Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatment
title_fullStr Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatment
title_full_unstemmed Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatment
title_short Structural or functional abnormality of sphincter of Oddi: an important factor for the recurrence of choledocholithiasis after endoscopic treatment
title_sort structural or functional abnormality of sphincter of oddi an important factor for the recurrence of choledocholithiasis after endoscopic treatment
topic Choledocholithiasis
endoscopic treatment
sphincter of Oddi
recurrence
url https://www.tandfonline.com/doi/10.1080/07853890.2024.2440119
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AT shuodongwu structuralorfunctionalabnormalityofsphincterofoddianimportantfactorfortherecurrenceofcholedocholithiasisafterendoscopictreatment
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