Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic Wounds
This work focuses on a capacitive biosensor based on a hydride peptide for the detection of MMP-13. Indeed, the enzyme MMP-13 is a remarkable indicator of inflammation in chronic wounds. To achieve specific detection of this enzyme, a metallocene was added to the peptide which amplifies the electric...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-04-01
|
| Series: | Proceedings |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2504-3900/97/1/183 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850058535514144768 |
|---|---|
| author | Amandine Sandoval Brice Sorli Arnaud Vena Cécile Echalier Ahmad Mehdi Gilles Subra |
| author_facet | Amandine Sandoval Brice Sorli Arnaud Vena Cécile Echalier Ahmad Mehdi Gilles Subra |
| author_sort | Amandine Sandoval |
| collection | DOAJ |
| description | This work focuses on a capacitive biosensor based on a hydride peptide for the detection of MMP-13. Indeed, the enzyme MMP-13 is a remarkable indicator of inflammation in chronic wounds. To achieve specific detection of this enzyme, a metallocene was added to the peptide which amplifies the electrical variation allowing for proof of concept and reliability. |
| format | Article |
| id | doaj-art-fe91bb7a3f314cde9c7cb1a153a77fc7 |
| institution | DOAJ |
| issn | 2504-3900 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Proceedings |
| spelling | doaj-art-fe91bb7a3f314cde9c7cb1a153a77fc72025-08-20T02:51:07ZengMDPI AGProceedings2504-39002024-04-0197118310.3390/proceedings2024097183Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic WoundsAmandine Sandoval0Brice Sorli1Arnaud Vena2Cécile Echalier3Ahmad Mehdi4Gilles Subra5IES, Université de Montpellier, CNRS, 34090 Montpellier, FranceIES, Université de Montpellier, CNRS, 34090 Montpellier, FranceIES, Université de Montpellier, CNRS, 34090 Montpellier, FranceIBMM, Université de Montpellier, CNRS, ENSCM, 34293 Montpellier, FranceICGM, Université de Montpellier, CNRS, ENSCM, 34293 Montpellier, FranceIBMM, Université de Montpellier, CNRS, ENSCM, 34293 Montpellier, FranceThis work focuses on a capacitive biosensor based on a hydride peptide for the detection of MMP-13. Indeed, the enzyme MMP-13 is a remarkable indicator of inflammation in chronic wounds. To achieve specific detection of this enzyme, a metallocene was added to the peptide which amplifies the electrical variation allowing for proof of concept and reliability.https://www.mdpi.com/2504-3900/97/1/183hybrid peptidesol–gelenzymatic activitycapacitance biosensor |
| spellingShingle | Amandine Sandoval Brice Sorli Arnaud Vena Cécile Echalier Ahmad Mehdi Gilles Subra Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic Wounds Proceedings hybrid peptide sol–gel enzymatic activity capacitance biosensor |
| title | Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic Wounds |
| title_full | Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic Wounds |
| title_fullStr | Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic Wounds |
| title_full_unstemmed | Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic Wounds |
| title_short | Capacitive Biosensor Based on a Peptide Hybrid Substrate for the Detection of MMP-13 in Chronic Wounds |
| title_sort | capacitive biosensor based on a peptide hybrid substrate for the detection of mmp 13 in chronic wounds |
| topic | hybrid peptide sol–gel enzymatic activity capacitance biosensor |
| url | https://www.mdpi.com/2504-3900/97/1/183 |
| work_keys_str_mv | AT amandinesandoval capacitivebiosensorbasedonapeptidehybridsubstrateforthedetectionofmmp13inchronicwounds AT bricesorli capacitivebiosensorbasedonapeptidehybridsubstrateforthedetectionofmmp13inchronicwounds AT arnaudvena capacitivebiosensorbasedonapeptidehybridsubstrateforthedetectionofmmp13inchronicwounds AT cecileechalier capacitivebiosensorbasedonapeptidehybridsubstrateforthedetectionofmmp13inchronicwounds AT ahmadmehdi capacitivebiosensorbasedonapeptidehybridsubstrateforthedetectionofmmp13inchronicwounds AT gillessubra capacitivebiosensorbasedonapeptidehybridsubstrateforthedetectionofmmp13inchronicwounds |