Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency

Congenital adrenal hyperplasia (CAH) is a group of inherited defects of cortisol biosynthesis. A case of classical CAH due to 21-hydroxylase deficiency (21-OHD) with early onset of salt waste and concurrence of meningomyelocele (MMC) was presented here. The management of salt-wasting crisis which is...

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Main Authors: Heves Kırmızıbekmez, Rahime Gül Yesiltepe Mutlu, Serdar Moralıoğlu, Ahmet Tellioğlu, Ayşenur Cerrah Celayir
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2015/196374
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author Heves Kırmızıbekmez
Rahime Gül Yesiltepe Mutlu
Serdar Moralıoğlu
Ahmet Tellioğlu
Ayşenur Cerrah Celayir
author_facet Heves Kırmızıbekmez
Rahime Gül Yesiltepe Mutlu
Serdar Moralıoğlu
Ahmet Tellioğlu
Ayşenur Cerrah Celayir
author_sort Heves Kırmızıbekmez
collection DOAJ
description Congenital adrenal hyperplasia (CAH) is a group of inherited defects of cortisol biosynthesis. A case of classical CAH due to 21-hydroxylase deficiency (21-OHD) with early onset of salt waste and concurrence of meningomyelocele (MMC) was presented here. The management of salt-wasting crisis which is complicated by a postrenal dysfunction due to neurogenic bladder was described. Possible reasons of growth retardation in the one-year follow-up period were discussed. A significant regression of the phallus with proper medical treatment was also mentioned.
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institution OA Journals
issn 2090-6803
2090-6811
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publishDate 2015-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-fe8fddac671b4b9abe315cce4b68421f2025-08-20T02:22:32ZengWileyCase Reports in Pediatrics2090-68032090-68112015-01-01201510.1155/2015/196374196374Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase DeficiencyHeves Kırmızıbekmez0Rahime Gül Yesiltepe Mutlu1Serdar Moralıoğlu2Ahmet Tellioğlu3Ayşenur Cerrah Celayir4Pediatric Endocrinology, Zeynep Kamil Obstetrics and Pediatrics Education and Research Hospital, 34668 Istanbul, TurkeyPediatric Endocrinology, Zeynep Kamil Obstetrics and Pediatrics Education and Research Hospital, 34668 Istanbul, TurkeyPediatric Surgery, Zeynep Kamil Obstetrics and Pediatrics Education and Research Hospital, 34668 Istanbul, TurkeyDepartment of Pediatrics, Zeynep Kamil Obstetrics and Pediatrics Education and Research Hospital, 34668 Istanbul, TurkeyPediatric Surgery, Zeynep Kamil Obstetrics and Pediatrics Education and Research Hospital, 34668 Istanbul, TurkeyCongenital adrenal hyperplasia (CAH) is a group of inherited defects of cortisol biosynthesis. A case of classical CAH due to 21-hydroxylase deficiency (21-OHD) with early onset of salt waste and concurrence of meningomyelocele (MMC) was presented here. The management of salt-wasting crisis which is complicated by a postrenal dysfunction due to neurogenic bladder was described. Possible reasons of growth retardation in the one-year follow-up period were discussed. A significant regression of the phallus with proper medical treatment was also mentioned.http://dx.doi.org/10.1155/2015/196374
spellingShingle Heves Kırmızıbekmez
Rahime Gül Yesiltepe Mutlu
Serdar Moralıoğlu
Ahmet Tellioğlu
Ayşenur Cerrah Celayir
Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
Case Reports in Pediatrics
title Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
title_full Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
title_fullStr Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
title_full_unstemmed Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
title_short Concurrence of Meningomyelocele and Salt-Wasting Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
title_sort concurrence of meningomyelocele and salt wasting congenital adrenal hyperplasia due to 21 hydroxylase deficiency
url http://dx.doi.org/10.1155/2015/196374
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