Improved Differentiation Towards Insulin Producing Beta-Cells Derived from Healthy Canine Pancreatic Ductal Organoids

Improved Differentiation Towards Insulin Producing Beta-Cells Derived from Healthy Canine Pancreatic Ductal Organoids

Background: Diabetes mellitus (DM) is a common potentially life-threatening endocrine disorder in pets and humans. Since only symptomatic treatment is available, a more sustainable treatment is urgently needed. Objective: The aim of this study is to establish functional differentiated canine pancrea...

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Bibliographic Details
Main Authors: Boyd H. T. Gouw, Flavia C. M. Oliveira, Hans S. Kooistra, Bart Spee, Lisa van Uden, Louis C. Penning
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Veterinary Sciences
Subjects:
diabetes mellitus
pancreatic differentiation
pancreatic stem cells
dog
organoids
Online Access:https://www.mdpi.com/2306-7381/12/4/362
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