Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf Extract
Ocimum sanctum (OS) Linn, is a medicinal herb that has been used in traditional medicine science ancient time. It contains an array of complex and diverse biologically active phytochemical constituents that can act as a reducing and stabilizing agent for synthesizing metal nanoparticles (NPs). Herei...
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| Format: | Article |
| Language: | English |
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Tamkang University Press
2025-03-01
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| Series: | Journal of Applied Science and Engineering |
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| Online Access: | http://jase.tku.edu.tw/articles/jase-202510-28-10-0006 |
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| author | Malik Ahmad Al-Natour Mohammad Faiyaz Anwar Shah Alam Khan Mohammad Changez |
| author_facet | Malik Ahmad Al-Natour Mohammad Faiyaz Anwar Shah Alam Khan Mohammad Changez |
| author_sort | Malik Ahmad Al-Natour |
| collection | DOAJ |
| description | Ocimum sanctum (OS) Linn, is a medicinal herb that has been used in traditional medicine science ancient time. It contains an array of complex and diverse biologically active phytochemical constituents that can act as a reducing and stabilizing agent for synthesizing metal nanoparticles (NPs). Herein, OS aqueous leaf extract was used to synthesize eco-friendly round and rod-shaped Ag NPs. The synthesized spherical and rod-shaped Ag NPs were analyzed by indirect methods by analysis of plasma band (UV-vis spectra) and thin films X-ray diffraction (XRD) peaks. Whereas, for direct methods, morphologies of synthesized Ag NPs were recoded using HR-TEM. Ag NPs demonstrated dose-dependent antibacterial efficacy against bacteria ( S. aureus). The MIC
and MBC values of spherical Ag NPs against 106CFU/mL of S. aureus were found to be 2.74 and 3.80µ g/mL, respectively. However, MIC and MBC values of Ag nano-rod were observed at 7.20µ g/mL and 13µ g/mL, respectively. SEM micrographs indicate that morphologies of spherical shape and nano-rod Ag NPs treated S. aureus showed breakdown, merge, and elongated morphologies with the presence of Ag NPs (nano-rod) inside of the S. aureus. |
| format | Article |
| id | doaj-art-fe7e301a34b148999eaf2f917b7f1596 |
| institution | DOAJ |
| issn | 2708-9967 2708-9975 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Tamkang University Press |
| record_format | Article |
| series | Journal of Applied Science and Engineering |
| spelling | doaj-art-fe7e301a34b148999eaf2f917b7f15962025-08-20T03:16:06ZengTamkang University PressJournal of Applied Science and Engineering2708-99672708-99752025-03-0128101929193710.6180/jase.202510_28(10).0006Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf ExtractMalik Ahmad Al-Natour0Mohammad Faiyaz Anwar1Shah Alam Khan2Mohammad Changez3College of Health Sciences, University of Buraimi, OmanDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, National University of Science and Technology, Muscat, OmanResearch, Innovation, and Entrepreneurship Unit, University of Buraimi, OmanOcimum sanctum (OS) Linn, is a medicinal herb that has been used in traditional medicine science ancient time. It contains an array of complex and diverse biologically active phytochemical constituents that can act as a reducing and stabilizing agent for synthesizing metal nanoparticles (NPs). Herein, OS aqueous leaf extract was used to synthesize eco-friendly round and rod-shaped Ag NPs. The synthesized spherical and rod-shaped Ag NPs were analyzed by indirect methods by analysis of plasma band (UV-vis spectra) and thin films X-ray diffraction (XRD) peaks. Whereas, for direct methods, morphologies of synthesized Ag NPs were recoded using HR-TEM. Ag NPs demonstrated dose-dependent antibacterial efficacy against bacteria ( S. aureus). The MIC and MBC values of spherical Ag NPs against 106CFU/mL of S. aureus were found to be 2.74 and 3.80µ g/mL, respectively. However, MIC and MBC values of Ag nano-rod were observed at 7.20µ g/mL and 13µ g/mL, respectively. SEM micrographs indicate that morphologies of spherical shape and nano-rod Ag NPs treated S. aureus showed breakdown, merge, and elongated morphologies with the presence of Ag NPs (nano-rod) inside of the S. aureus.http://jase.tku.edu.tw/articles/jase-202510-28-10-0006green chemistryocimum sanctumstaphylococcus aureussilver nanoparticlestransmission electron microscopexrd |
| spellingShingle | Malik Ahmad Al-Natour Mohammad Faiyaz Anwar Shah Alam Khan Mohammad Changez Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf Extract Journal of Applied Science and Engineering green chemistry ocimum sanctum staphylococcus aureus silver nanoparticles transmission electron microscope xrd |
| title | Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf Extract |
| title_full | Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf Extract |
| title_fullStr | Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf Extract |
| title_full_unstemmed | Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf Extract |
| title_short | Characterization and Antimicrobial Activity of Silverrods Nano: Synthesized in Green Ocimum sanctum Leaf Extract |
| title_sort | characterization and antimicrobial activity of silverrods nano synthesized in green ocimum sanctum leaf extract |
| topic | green chemistry ocimum sanctum staphylococcus aureus silver nanoparticles transmission electron microscope xrd |
| url | http://jase.tku.edu.tw/articles/jase-202510-28-10-0006 |
| work_keys_str_mv | AT malikahmadalnatour characterizationandantimicrobialactivityofsilverrodsnanosynthesizedingreenocimumsanctumleafextract AT mohammadfaiyazanwar characterizationandantimicrobialactivityofsilverrodsnanosynthesizedingreenocimumsanctumleafextract AT shahalamkhan characterizationandantimicrobialactivityofsilverrodsnanosynthesizedingreenocimumsanctumleafextract AT mohammadchangez characterizationandantimicrobialactivityofsilverrodsnanosynthesizedingreenocimumsanctumleafextract |