zMAP toolset: model-based analysis of large-scale proteomic data via a variance stabilizing z-transformation

zMAP toolset: model-based analysis of large-scale proteomic data via a variance stabilizing z-transformation

Abstract Isobaric labeling-based mass spectrometry (ILMS) has been widely used to quantify, on a proteome-wide scale, the relative protein abundance in different biological conditions. However, large-scale ILMS data sets typically involve multiple runs of mass spectrometry, bringing great computatio...

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Main Authors: Xiuqi Gui, Jing Huang, Linjie Ruan, Yanjun Wu, Xuan Guo, Ruifang Cao, Shuhan Zhou, Fengxiang Tan, Hongwen Zhu, Mushan Li, Guoqing Zhang, Hu Zhou, Lixing Zhan, Xin Liu, Shiqi Tu, Zhen Shao
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-024-03382-9
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