Circulating BCKAs are closely associated with adipose tissue insulin resistance in type 2 diabetes

Circulating BCKAs are closely associated with adipose tissue insulin resistance in type 2 diabetes

Abstract Background This study aimed to examine the association between branched-chain amino acids/branched-chain α-keto acids (BCAAs/BCKAs) and adipose tissue insulin resistance (Adipo-IR) in patients with type 2 diabetes mellitus (T2DM). Methods A total of 506 patients with T2DM were included in t...

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Bibliographic Details
Main Authors: Jie Gao, Mai Re YanMu Rouzi, Haofan Yang, Wenhao Zheng, Liang Wang, Tao Lei, Jun Lu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Adipose tissue
Insulin resistance
Branched-chain amino acid
Type 2 diabetes mellitus
Online Access:https://doi.org/10.1186/s13098-025-01860-z
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