Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)

Introduction. The mucociliary apparatus (MCA) of the fallopian tubes (MTр) represents one of the key mechanisms and arms in functioning of female reproductive system. A prominent role of impaired MCA in the pathogenesis of reproductive system diseases and infertility, on the one hand, as well as ins...

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Main Author: V. I. Kobylyansky
Format: Article
Language:Russian
Published: IRBIS LLC 2021-11-01
Series:Акушерство, гинекология и репродукция
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Online Access:https://www.gynecology.su/jour/article/view/1128
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author V. I. Kobylyansky
author_facet V. I. Kobylyansky
author_sort V. I. Kobylyansky
collection DOAJ
description Introduction. The mucociliary apparatus (MCA) of the fallopian tubes (MTр) represents one of the key mechanisms and arms in functioning of female reproductive system. A prominent role of impaired MCA in the pathogenesis of reproductive system diseases and infertility, on the one hand, as well as insufficient knowledge and elucidation of this topic, on the other hand, spurred current study.Aim: to improve our understanding about a role for reproductive system MCA and its impairment in developing diseases and infertility, as well as to identify potential perspectives for their correction.Materials and Methods. We searched for publications and analyzed literature data from 1980 to 2020 using various scientific databases, including Index Medicus, PubMed/MEDLINE, Embase, Cochrane Library and Russian scholarly journals related to gynecology, obstetrics and reproduction.Results. The analysis conducted allowed to originally assess the morpho-functional, structural-genetic features and other important aspects of MCA MTр. In addition, we demonstrated an impact of various factors on developing diverse types of pathological processes, including those capable of causing infertility. Moreover, we also elucidated a state of MCA MTр coupled to various diseases, including genetically determined disorders.Conclusion. The role of impaired MCA MTр in developing pathological process and infertility was of tremendous importance and deserves close attention, because they are often remained undiagnosed by standard methods and require use of morphological and functional research methods for verification. Perspectives for diagnostics and correction of MCA MTр disorders are further discussed.
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spelling doaj-art-fe6c2011cdc84989be8f05a6dc9e58382025-08-20T03:57:37ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942021-11-0115558659810.17749/2313-7347/ob.gyn.rep.2021.166679Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)V. I. Kobylyansky0Federal Pulmonology Research Institute, Federal Medical and Biological Agency of RussiaIntroduction. The mucociliary apparatus (MCA) of the fallopian tubes (MTр) represents one of the key mechanisms and arms in functioning of female reproductive system. A prominent role of impaired MCA in the pathogenesis of reproductive system diseases and infertility, on the one hand, as well as insufficient knowledge and elucidation of this topic, on the other hand, spurred current study.Aim: to improve our understanding about a role for reproductive system MCA and its impairment in developing diseases and infertility, as well as to identify potential perspectives for their correction.Materials and Methods. We searched for publications and analyzed literature data from 1980 to 2020 using various scientific databases, including Index Medicus, PubMed/MEDLINE, Embase, Cochrane Library and Russian scholarly journals related to gynecology, obstetrics and reproduction.Results. The analysis conducted allowed to originally assess the morpho-functional, structural-genetic features and other important aspects of MCA MTр. In addition, we demonstrated an impact of various factors on developing diverse types of pathological processes, including those capable of causing infertility. Moreover, we also elucidated a state of MCA MTр coupled to various diseases, including genetically determined disorders.Conclusion. The role of impaired MCA MTр in developing pathological process and infertility was of tremendous importance and deserves close attention, because they are often remained undiagnosed by standard methods and require use of morphological and functional research methods for verification. Perspectives for diagnostics and correction of MCA MTр disorders are further discussed.https://www.gynecology.su/jour/article/view/1128mucociliary apparatusmcamucociliary systemfallopian tubescilia and mucus of the fallopian tubesdisorders and infertility
spellingShingle V. I. Kobylyansky
Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)
Акушерство, гинекология и репродукция
mucociliary apparatus
mca
mucociliary system
fallopian tubes
cilia and mucus of the fallopian tubes
disorders and infertility
title Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)
title_full Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)
title_fullStr Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)
title_full_unstemmed Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)
title_short Mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction (analytical review)
title_sort mucociliary apparatus of the fallopian tubes and related pathogenetic aspects contributing to infertility and prospects for correction analytical review
topic mucociliary apparatus
mca
mucociliary system
fallopian tubes
cilia and mucus of the fallopian tubes
disorders and infertility
url https://www.gynecology.su/jour/article/view/1128
work_keys_str_mv AT vikobylyansky mucociliaryapparatusofthefallopiantubesandrelatedpathogeneticaspectscontributingtoinfertilityandprospectsforcorrectionanalyticalreview