Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar region

Background. Myocardial infarction (MI) without obstructive lesion of coronary arteries (MINOCA) has incidence  to 14%. Despite its high prevalence,  MINOCA is paid not enough attention, therefore some patients can not receive appropriate treatment.Aim. Evaluating the long-term results of clinical ob...

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Main Authors: S. V. Kruchinova, E. D. Kosmacheva, S. A. Raff, Z. G. Tatarintseva, V. A. Porhanov
Format: Article
Language:English
Published: Scientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1 2019-06-01
Series:Инновационная медицина Кубани
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Online Access:https://www.innovmedkub.ru/jour/article/view/190
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author S. V. Kruchinova
E. D. Kosmacheva
S. A. Raff
Z. G. Tatarintseva
V. A. Porhanov
author_facet S. V. Kruchinova
E. D. Kosmacheva
S. A. Raff
Z. G. Tatarintseva
V. A. Porhanov
author_sort S. V. Kruchinova
collection DOAJ
description Background. Myocardial infarction (MI) without obstructive lesion of coronary arteries (MINOCA) has incidence  to 14%. Despite its high prevalence,  MINOCA is paid not enough attention, therefore some patients can not receive appropriate treatment.Aim. Evaluating the long-term results of clinical observation in patients with MINOCA  in comparison with patients with obstructive damage and the subsequent revascularization of myocardium.Material and methods. On the basis of Scientific Research Institute RCH – 1 the multicenter cohort observation was organized. Patients from the register CROCS (the register of acute coronary syndrome in Krasnodar region) with the  diagnosis MI were divided into two groups: MINOCA including patients without obstructive damage of coronary arteries and MINOCA including patients with obstructive injury and the subsequent stenting a heart attack connected artery. All patients in 12 months would have control assessment during which they had objective survey; electrocardiography; daily monitoring; test of six-minute walking, echocardiography. Results. In the MINOCA group in 12 months after the acute coronary event in 21.5% cases there were tension stenocardia, in 16.2% – a painless form of myocardial ischemia was revealed, in a group of patients with MINOCA stenocardia of tension was revealed at 12.5% and 8.4% – with painless ischemia. The group of patients with MINOCA is characterized  by more reliable decrease in both parameters of heart rate variability, and turbulence of heart rate. MINOCA is followed by statistically significant increase in risk of ACS development and death within 12 months. All indicators had reliable difference.Conclusion. Patients with MINOCA are a special group, their differential characteristics demand definite diagnostic efforts.
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spelling doaj-art-fe693bdb5e6648ef8196671b7e2e36352025-08-20T03:47:32ZengScientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1Инновационная медицина Кубани2541-98972019-06-010261210.35401/2500-0268-2019-14-2-6-12183Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar regionS. V. Kruchinova0E. D. Kosmacheva1S. A. Raff2Z. G. Tatarintseva3V. A. Porhanov4Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1; Kuban State Medical UniversityScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1; Kuban State Medical UniversityScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1; Kuban State Medical UniversityBackground. Myocardial infarction (MI) without obstructive lesion of coronary arteries (MINOCA) has incidence  to 14%. Despite its high prevalence,  MINOCA is paid not enough attention, therefore some patients can not receive appropriate treatment.Aim. Evaluating the long-term results of clinical observation in patients with MINOCA  in comparison with patients with obstructive damage and the subsequent revascularization of myocardium.Material and methods. On the basis of Scientific Research Institute RCH – 1 the multicenter cohort observation was organized. Patients from the register CROCS (the register of acute coronary syndrome in Krasnodar region) with the  diagnosis MI were divided into two groups: MINOCA including patients without obstructive damage of coronary arteries and MINOCA including patients with obstructive injury and the subsequent stenting a heart attack connected artery. All patients in 12 months would have control assessment during which they had objective survey; electrocardiography; daily monitoring; test of six-minute walking, echocardiography. Results. In the MINOCA group in 12 months after the acute coronary event in 21.5% cases there were tension stenocardia, in 16.2% – a painless form of myocardial ischemia was revealed, in a group of patients with MINOCA stenocardia of tension was revealed at 12.5% and 8.4% – with painless ischemia. The group of patients with MINOCA is characterized  by more reliable decrease in both parameters of heart rate variability, and turbulence of heart rate. MINOCA is followed by statistically significant increase in risk of ACS development and death within 12 months. All indicators had reliable difference.Conclusion. Patients with MINOCA are a special group, their differential characteristics demand definite diagnostic efforts.https://www.innovmedkub.ru/jour/article/view/190myocardial infarction without obstructive lesion of coronary arteriesregister
spellingShingle S. V. Kruchinova
E. D. Kosmacheva
S. A. Raff
Z. G. Tatarintseva
V. A. Porhanov
Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar region
Инновационная медицина Кубани
myocardial infarction without obstructive lesion of coronary arteries
register
title Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar region
title_full Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar region
title_fullStr Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar region
title_full_unstemmed Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar region
title_short Results of dynamic follow-up for patients with myocardial infarction without obstructive lesion of coronary arteries: data of the overall register for acute coronary syndrome in Krasnodar region
title_sort results of dynamic follow up for patients with myocardial infarction without obstructive lesion of coronary arteries data of the overall register for acute coronary syndrome in krasnodar region
topic myocardial infarction without obstructive lesion of coronary arteries
register
url https://www.innovmedkub.ru/jour/article/view/190
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