PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO)
The development of cervical cancer is associated with high-risk Human papilloma viruses (HPV-HR). In sub-Saharan Africa cervical cancer is the most common cancer among women and the leading cause of death attributed to malignant tumors. This study aims to identify HPV genotypes within the 30'...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2013-09-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/451 |
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| author | Theodora M. Zohoncon Jacques Simpore |
| author_facet | Theodora M. Zohoncon Jacques Simpore |
| author_sort | Theodora M. Zohoncon |
| collection | DOAJ |
| description | The development of cervical cancer is associated with high-risk Human papilloma viruses (HPV-HR). In sub-Saharan Africa cervical cancer is the most common cancer among women and the leading cause of death attributed to malignant tumors. This study aims to identify HPV genotypes within the 30'S and 50'S HPV families found in two previous studies from our laboratory, and to determine the prevalence of twelve HPV-HR genotypes in a population of women in Ouagadougou.
The twelve HPV-HR genotypes were determined by real-time multiplex PCR, in 180 samples from the general population and among a group of HIV-1 infected women.
The most common genotypes found were HPV 35 (29.4%) and HPV 31 (26.1%) of the 30’S family, and HPV 52 (29.4%) and HPV 58 (20.6%) of the 50'S family. Multiple infections of HPV-HR were observed in 78.03% of infected women.
The frequencies of HPV genotypes from the 30'S and 50'S families were higher, while the genotypes HPV-16 and18 were lower among the women in our study. |
| format | Article |
| id | doaj-art-fe61a100b43c4a6db7fd78e1bf84527e |
| institution | DOAJ |
| issn | 2035-3006 |
| language | English |
| publishDate | 2013-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-fe61a100b43c4a6db7fd78e1bf84527e2025-08-20T02:51:59ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062013-09-0151e2013059e201305910.4084/mjhid.2013.059343PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO)Theodora M. ZohonconJacques SimporeThe development of cervical cancer is associated with high-risk Human papilloma viruses (HPV-HR). In sub-Saharan Africa cervical cancer is the most common cancer among women and the leading cause of death attributed to malignant tumors. This study aims to identify HPV genotypes within the 30'S and 50'S HPV families found in two previous studies from our laboratory, and to determine the prevalence of twelve HPV-HR genotypes in a population of women in Ouagadougou. The twelve HPV-HR genotypes were determined by real-time multiplex PCR, in 180 samples from the general population and among a group of HIV-1 infected women. The most common genotypes found were HPV 35 (29.4%) and HPV 31 (26.1%) of the 30’S family, and HPV 52 (29.4%) and HPV 58 (20.6%) of the 50'S family. Multiple infections of HPV-HR were observed in 78.03% of infected women. The frequencies of HPV genotypes from the 30'S and 50'S families were higher, while the genotypes HPV-16 and18 were lower among the women in our study.http://www.mjhid.org/index.php/mjhid/article/view/451Cervical cancer, multiplex real time PCR, HIV, Burkina Faso |
| spellingShingle | Theodora M. Zohoncon Jacques Simpore PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO) Mediterranean Journal of Hematology and Infectious Diseases Cervical cancer, multiplex real time PCR, HIV, Burkina Faso |
| title | PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO) |
| title_full | PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO) |
| title_fullStr | PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO) |
| title_full_unstemmed | PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO) |
| title_short | PREVALENCE OF HPV HIGH-RISK GENOTYPES IN THREE COHORTS OF WOMEN IN OUAGADOUGOU (BURKINA FASO) |
| title_sort | prevalence of hpv high risk genotypes in three cohorts of women in ouagadougou burkina faso |
| topic | Cervical cancer, multiplex real time PCR, HIV, Burkina Faso |
| url | http://www.mjhid.org/index.php/mjhid/article/view/451 |
| work_keys_str_mv | AT theodoramzohoncon prevalenceofhpvhighriskgenotypesinthreecohortsofwomeninouagadougouburkinafaso AT jacquessimpore prevalenceofhpvhighriskgenotypesinthreecohortsofwomeninouagadougouburkinafaso |