Tea and Recurrent Clostridium difficile Infection

Background and Aims. Studies have shown effects of diet on gut microbiota. We aimed to identify foods associated with recurrent Clostridium difficile infection (CDI). Methods. In this cross-sectional survey, consecutive patients diagnosed with CDI were identified by electronic medical records. Colit...

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Main Authors: Martin Oman Evans II, Brad Starley, Jack Carl Galagan, Joseph Michael Yabes, Sara Evans, Joseph John Salama
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/4514687
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author Martin Oman Evans II
Brad Starley
Jack Carl Galagan
Joseph Michael Yabes
Sara Evans
Joseph John Salama
author_facet Martin Oman Evans II
Brad Starley
Jack Carl Galagan
Joseph Michael Yabes
Sara Evans
Joseph John Salama
author_sort Martin Oman Evans II
collection DOAJ
description Background and Aims. Studies have shown effects of diet on gut microbiota. We aimed to identify foods associated with recurrent Clostridium difficile infection (CDI). Methods. In this cross-sectional survey, consecutive patients diagnosed with CDI were identified by electronic medical records. Colitis symptoms and positive Clostridium difficile assay were confirmed. Health-care onset-health-care facility associated CDI was excluded. Food surveys were mailed to 411 patients. Survey responses served as the primary outcome measure. Spearman’s rank correlation identified risk factors for CDI recurrence. Results. Surveys were returned by 68 patients. Nineteen patients experienced CDI recurrence. Compared to patients without CDI recurrence, patients with CDI recurrence had more antibiotics prescribed preceding their infection (p=0.003). Greater numbers of the latter also listed tea (p=0.002), coffee (p=0.013), and eggs (p=0.013), on their 24-hour food recall. Logistic regression identified tea as the only food risk factor for CDI recurrence (adjusted OR: 5.71; 95% CI: 1.26–25.89). Conclusion. The present results indicate a possible association between tea and CDI recurrence. Additional studies are needed to characterize and confirm this association.
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series Gastroenterology Research and Practice
spelling doaj-art-fe60ba2ac54049beb69458396849e4e52025-08-20T02:22:34ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/45146874514687Tea and Recurrent Clostridium difficile InfectionMartin Oman Evans II0Brad Starley1Jack Carl Galagan2Joseph Michael Yabes3Sara Evans4Joseph John Salama5Department of Internal Medicine, Novosel Aviation Clinic, Fort Riley, KS, USADepartment of Gastroenterology, St. Luke's Clinic, Twin Falls, ID, USADepartment of Internal Medicine, San Antonio Military Medical Center, San Antonio, TX, USADepartment of Internal Medicine, San Antonio Military Medical Center, San Antonio, TX, USAPhysical Medicine and Rehabilitation, Larkin Community Hospital, South Miami, FL, USANovosel Aviation Clinic, Fort Riley, KS, USABackground and Aims. Studies have shown effects of diet on gut microbiota. We aimed to identify foods associated with recurrent Clostridium difficile infection (CDI). Methods. In this cross-sectional survey, consecutive patients diagnosed with CDI were identified by electronic medical records. Colitis symptoms and positive Clostridium difficile assay were confirmed. Health-care onset-health-care facility associated CDI was excluded. Food surveys were mailed to 411 patients. Survey responses served as the primary outcome measure. Spearman’s rank correlation identified risk factors for CDI recurrence. Results. Surveys were returned by 68 patients. Nineteen patients experienced CDI recurrence. Compared to patients without CDI recurrence, patients with CDI recurrence had more antibiotics prescribed preceding their infection (p=0.003). Greater numbers of the latter also listed tea (p=0.002), coffee (p=0.013), and eggs (p=0.013), on their 24-hour food recall. Logistic regression identified tea as the only food risk factor for CDI recurrence (adjusted OR: 5.71; 95% CI: 1.26–25.89). Conclusion. The present results indicate a possible association between tea and CDI recurrence. Additional studies are needed to characterize and confirm this association.http://dx.doi.org/10.1155/2016/4514687
spellingShingle Martin Oman Evans II
Brad Starley
Jack Carl Galagan
Joseph Michael Yabes
Sara Evans
Joseph John Salama
Tea and Recurrent Clostridium difficile Infection
Gastroenterology Research and Practice
title Tea and Recurrent Clostridium difficile Infection
title_full Tea and Recurrent Clostridium difficile Infection
title_fullStr Tea and Recurrent Clostridium difficile Infection
title_full_unstemmed Tea and Recurrent Clostridium difficile Infection
title_short Tea and Recurrent Clostridium difficile Infection
title_sort tea and recurrent clostridium difficile infection
url http://dx.doi.org/10.1155/2016/4514687
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