Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhus
Thrombocytopenia is a common manifestation of rickettsial disease. Immune thrombocytopenic purpura (ITP) is an acquired thrombocytopenia with antibodies detected against platelet surface antigens. It is the most common cause of acute-onset thrombocytopenia in an otherwise healthy child. ITP secondar...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Journal of Current Research in Scientific Medicine |
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| Online Access: | https://journals.lww.com/10.4103/jcrsm.jcrsm_96_24 |
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| author | Jency Auxilia Nivya Jeet Daniel Nishanth Rajan |
| author_facet | Jency Auxilia Nivya Jeet Daniel Nishanth Rajan |
| author_sort | Jency Auxilia |
| collection | DOAJ |
| description | Thrombocytopenia is a common manifestation of rickettsial disease. Immune thrombocytopenic purpura (ITP) is an acquired thrombocytopenia with antibodies detected against platelet surface antigens. It is the most common cause of acute-onset thrombocytopenia in an otherwise healthy child. ITP secondary to an underlying condition is a diagnosis of exclusion that is essential to establish treatment efficacy. Here, we report a case of immune thrombocytopenia secondary to scrub typhus infection, and we summarize its diagnosis and treatment. A 9-year-old boy was admitted to our hospital with hematuria, petechiae over both legs, and a history of fever for 11 days. Physical examination revealed the presence of an eschar over the left groin. Although thrombocytopenia is common in scrub typhus, failure of platelet counts to normalize even after medical management with doxycycline should prompt the clinician to consider other possibilities of thrombocytopenia, notably immune thrombocytopenia. |
| format | Article |
| id | doaj-art-fe6026d8ad3f422fbfe05e91a61cfe84 |
| institution | DOAJ |
| issn | 2542-6273 2455-3069 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Current Research in Scientific Medicine |
| spelling | doaj-art-fe6026d8ad3f422fbfe05e91a61cfe842025-08-20T02:42:25ZengWolters Kluwer Medknow PublicationsJournal of Current Research in Scientific Medicine2542-62732455-30692025-01-01111767810.4103/jcrsm.jcrsm_96_24Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhusJency AuxiliaNivya Jeet DanielNishanth RajanThrombocytopenia is a common manifestation of rickettsial disease. Immune thrombocytopenic purpura (ITP) is an acquired thrombocytopenia with antibodies detected against platelet surface antigens. It is the most common cause of acute-onset thrombocytopenia in an otherwise healthy child. ITP secondary to an underlying condition is a diagnosis of exclusion that is essential to establish treatment efficacy. Here, we report a case of immune thrombocytopenia secondary to scrub typhus infection, and we summarize its diagnosis and treatment. A 9-year-old boy was admitted to our hospital with hematuria, petechiae over both legs, and a history of fever for 11 days. Physical examination revealed the presence of an eschar over the left groin. Although thrombocytopenia is common in scrub typhus, failure of platelet counts to normalize even after medical management with doxycycline should prompt the clinician to consider other possibilities of thrombocytopenia, notably immune thrombocytopenia.https://journals.lww.com/10.4103/jcrsm.jcrsm_96_24doxycyclineimmune thrombocytopenic purpuraintravenous immune globulinscrub typhus |
| spellingShingle | Jency Auxilia Nivya Jeet Daniel Nishanth Rajan Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhus Journal of Current Research in Scientific Medicine doxycycline immune thrombocytopenic purpura intravenous immune globulin scrub typhus |
| title | Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhus |
| title_full | Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhus |
| title_fullStr | Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhus |
| title_full_unstemmed | Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhus |
| title_short | Secondary immune thrombocytopenic purpura: An unusual complication of scrub typhus |
| title_sort | secondary immune thrombocytopenic purpura an unusual complication of scrub typhus |
| topic | doxycycline immune thrombocytopenic purpura intravenous immune globulin scrub typhus |
| url | https://journals.lww.com/10.4103/jcrsm.jcrsm_96_24 |
| work_keys_str_mv | AT jencyauxilia secondaryimmunethrombocytopenicpurpuraanunusualcomplicationofscrubtyphus AT nivyajeetdaniel secondaryimmunethrombocytopenicpurpuraanunusualcomplicationofscrubtyphus AT nishanthrajan secondaryimmunethrombocytopenicpurpuraanunusualcomplicationofscrubtyphus |