Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations
A study of mechanisms of regulation of volume of erythrocytes in cardiosurgical patients with moderate (24 patients) and expressed (13 patients) hemolysis after coronary artery bypass grafting in conditions of cardiopulmonary bypass was carried out. It was established that development expressed hemo...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2012-12-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/860 |
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| author | S. P. Chumakova V. V. Novitsky O. I. Urazova I. V. Petrova V. M. Shipulin E. V. Saprykina O. A. Khokhlov |
| author_facet | S. P. Chumakova V. V. Novitsky O. I. Urazova I. V. Petrova V. M. Shipulin E. V. Saprykina O. A. Khokhlov |
| author_sort | S. P. Chumakova |
| collection | DOAJ |
| description | A study of mechanisms of regulation of volume of erythrocytes in cardiosurgical patients with moderate (24 patients) and expressed (13 patients) hemolysis after coronary artery bypass grafting in conditions of cardiopulmonary bypass was carried out. It was established that development expressed hemolysis is associated with higher (than under moderate hemolysis) volume of erythrocytes after operation, reduction Са2+-dependent К+-permeability and activity of Nа+/K+-ATPazy in their against deficiency of ATP in cells. At patients with moderated hemolysis independently of an investigation phase Са2+-dependent К+-permeability of a membrane of erythrocytes doesn't differ from healthy donors, but activity of Nа+/K+-ATPazy is reduced at the sufficient content of ATP. |
| format | Article |
| id | doaj-art-fe561e240e834ebfa34f4be5a4d062fb |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2012-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-fe561e240e834ebfa34f4be5a4d062fb2025-08-20T03:38:09ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-12-0111610610910.20538/1682-0363-2012-6-106-109654Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operationsS. P. Chumakova0V. V. Novitsky1O. I. Urazova2I. V. Petrova3V. M. Shipulin4E. V. Saprykina5O. A. Khokhlov6Сибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскНИИ кардиологии СО РАМН, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскA study of mechanisms of regulation of volume of erythrocytes in cardiosurgical patients with moderate (24 patients) and expressed (13 patients) hemolysis after coronary artery bypass grafting in conditions of cardiopulmonary bypass was carried out. It was established that development expressed hemolysis is associated with higher (than under moderate hemolysis) volume of erythrocytes after operation, reduction Са2+-dependent К+-permeability and activity of Nа+/K+-ATPazy in their against deficiency of ATP in cells. At patients with moderated hemolysis independently of an investigation phase Са2+-dependent К+-permeability of a membrane of erythrocytes doesn't differ from healthy donors, but activity of Nа+/K+-ATPazy is reduced at the sufficient content of ATP.https://bulletin.ssmu.ru/jour/article/view/860hemolysisvolume erythrocytesса2+-dependent к+-permeabilitynа+/k+-atpazyatpcardiopulmonary bypass |
| spellingShingle | S. P. Chumakova V. V. Novitsky O. I. Urazova I. V. Petrova V. M. Shipulin E. V. Saprykina O. A. Khokhlov Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations Бюллетень сибирской медицины hemolysis volume erythrocytes са2+-dependent к+-permeability nа+/k+-atpazy atp cardiopulmonary bypass |
| title | Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations |
| title_full | Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations |
| title_fullStr | Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations |
| title_full_unstemmed | Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations |
| title_short | Mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations |
| title_sort | mechanisms of regulation of erythrocytes volume in cardiosurgical patients with moderated and expressed the hemolysis after operations |
| topic | hemolysis volume erythrocytes са2+-dependent к+-permeability nа+/k+-atpazy atp cardiopulmonary bypass |
| url | https://bulletin.ssmu.ru/jour/article/view/860 |
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