Perindopril and indapamide combination effects on circadian blood pressure profile and cerebral hemodynamics in patients with arterial hypertension and stroke
Aim. To investigate the effects of perindopril and indapamide combination (Noliprel® forte) on circadian blood pressure profile (CBPP) and cerebral hemodynamics (CH) among patients in late post-ischemic stroke (IS) period. Material and methods. In total, 30 patients with arterial hypertension (AH) w...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2007-06-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1231 |
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| Summary: | Aim. To investigate the effects of perindopril and indapamide combination (Noliprel® forte) on circadian blood pressure profile (CBPP) and cerebral hemodynamics (CH) among patients in late post-ischemic stroke (IS) period. Material and methods. In total, 30 patients with arterial hypertension (AH) were examined, including 15 with previous IS. At baseline and 21 days later, neurological status and cognitive function assessment, experimental psychological examination, 24-hour BP monitoring, rheoencephalography, brachial and cerebral Doppler ultrasoundwere performed. Both groups received Noliprel® forte, 1-2 tablets, once per day. Results. Stroke in anamnesis substantially influenced CH and CBPP parameters in AH patients. Conclusion. Noliprel® forte is an effective antihypertensive medication, not only reducing BP, but also improving CH and cognitive function in patients with AH and stroke. |
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| ISSN: | 1728-8800 2619-0125 |