Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada Syndrome

Since it was first described approximately 15 years ago, the Brugada Syndrome has spurred a significant quantity of interest in its underlying mechanism and physiology. The Brugada electrocardiographic pattern is characterized by right bundle branch block morphology and ST segment elevations in the...

Full description

Saved in:
Bibliographic Details
Main Authors: John N. Makaryus, Jennifer Verbsky, Scott Schwarz, David Slotwiner
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2009/492031
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832556376318017536
author John N. Makaryus
Jennifer Verbsky
Scott Schwarz
David Slotwiner
author_facet John N. Makaryus
Jennifer Verbsky
Scott Schwarz
David Slotwiner
author_sort John N. Makaryus
collection DOAJ
description Since it was first described approximately 15 years ago, the Brugada Syndrome has spurred a significant quantity of interest in its underlying mechanism and physiology. The Brugada electrocardiographic pattern is characterized by right bundle branch block morphology and ST segment elevations in the right precordial leads with an absence of identifiable underlying structural heart disease. The syndrome is clinically significant since these patients are at a higher risk of developing malignant ventricular arrhythmias. One of the mechanisms behind the disorder involves mutations in specific myocardial sodium channels. Furthermore, these electrocardiographic changes appear to be temperature dependent. We present the case of a 35-year-old male who presented with intestinal Shigellosis and was also found to have Brugada-type electrocardiographic changes on ECG. The electrocardiographic changes that were present when the patient was admitted and febrile resolved following antibiotic therapy and defervescence.
format Article
id doaj-art-fe4bc17b43c2443d828914d61d611bb7
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2009-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-fe4bc17b43c2443d828914d61d611bb72025-02-03T05:45:39ZengWileyCase Reports in Medicine1687-96271687-96352009-01-01200910.1155/2009/492031492031Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada SyndromeJohn N. Makaryus0Jennifer Verbsky1Scott Schwarz2David Slotwiner3Department of Cardiology, North Shore-Long Island Jewish Health System, Manhasset, 270-05 76th Ave, New Hyde Park, NY 11040, USADepartment of Cardiology, North Shore-Long Island Jewish Health System, Manhasset, 270-05 76th Ave, New Hyde Park, NY 11040, USADepartment of Cardiology, North Shore-Long Island Jewish Health System, Manhasset, 270-05 76th Ave, New Hyde Park, NY 11040, USADepartment of Cardiology, North Shore-Long Island Jewish Health System, Manhasset, 270-05 76th Ave, New Hyde Park, NY 11040, USASince it was first described approximately 15 years ago, the Brugada Syndrome has spurred a significant quantity of interest in its underlying mechanism and physiology. The Brugada electrocardiographic pattern is characterized by right bundle branch block morphology and ST segment elevations in the right precordial leads with an absence of identifiable underlying structural heart disease. The syndrome is clinically significant since these patients are at a higher risk of developing malignant ventricular arrhythmias. One of the mechanisms behind the disorder involves mutations in specific myocardial sodium channels. Furthermore, these electrocardiographic changes appear to be temperature dependent. We present the case of a 35-year-old male who presented with intestinal Shigellosis and was also found to have Brugada-type electrocardiographic changes on ECG. The electrocardiographic changes that were present when the patient was admitted and febrile resolved following antibiotic therapy and defervescence.http://dx.doi.org/10.1155/2009/492031
spellingShingle John N. Makaryus
Jennifer Verbsky
Scott Schwarz
David Slotwiner
Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada Syndrome
Case Reports in Medicine
title Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada Syndrome
title_full Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada Syndrome
title_fullStr Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada Syndrome
title_full_unstemmed Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada Syndrome
title_short Fever Associated with Gastrointestinal Shigellosis Unmasks Probable Brugada Syndrome
title_sort fever associated with gastrointestinal shigellosis unmasks probable brugada syndrome
url http://dx.doi.org/10.1155/2009/492031
work_keys_str_mv AT johnnmakaryus feverassociatedwithgastrointestinalshigellosisunmasksprobablebrugadasyndrome
AT jenniferverbsky feverassociatedwithgastrointestinalshigellosisunmasksprobablebrugadasyndrome
AT scottschwarz feverassociatedwithgastrointestinalshigellosisunmasksprobablebrugadasyndrome
AT davidslotwiner feverassociatedwithgastrointestinalshigellosisunmasksprobablebrugadasyndrome