Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways
AIM: To investigate the functions and potential mechanisms of obtusifolin in dry eye disease (DED) in a rat model. METHODS: A rat DED model was established via topical administration of benzalkonium chloride (BAC), followed by administration of obtusifolin. Conjunctival irritation score and tear pro...
Saved in:
| Main Authors: | Dan Zhu, Xiao-Yang Wu, Liang-Chang Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2025-08-01
|
| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/en_publish/2025/8/20250802.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A novel carboxamide bromodomain inhibitor attenuates osteoarthritis via epigenetic repression of NF-κB and MAPK signaling
by: Hyemi Lee, et al.
Published: (2025-07-01) -
IL-37 inhibited inflammation to improve gestational diabetes mellitus through the GSK3/NF-κB pathway
by: Meiyu Song, et al.
Published: (2025-06-01) -
Assessment of Efficiency of Dry Eye Therapy in Diabetes
by: F. A. Bahritdinova, et al.
Published: (2022-07-01) -
Prevalence of Dry Eye Disease in an Urban Community
by: Kevin Matthew Serafin B. Panggat, MD, et al.
Published: (2015-06-01) -
Investigating Mask-Associated Dry Eye and Contributing Factors in Healthcare Providers
by: Park KS, et al.
Published: (2025-04-01)