SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEX
Web-service SNP_TATA_Comparator has been developed for using experimentally proven in silico evaluation of in vivo biochemical manifestations of SNPs in the core promoter regions of human genes associated with diseases on the base of the TBP/TATA complex equilibrium equation (TBP is TATA binding pro...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2015-01-01
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| Series: | Вавиловский журнал генетики и селекции |
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| Online Access: | https://vavilov.elpub.ru/jour/article/view/183 |
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| author | D. A. Rasskazov K. V. Gunbin P. M. Ponomarenko O. V. Vishnevsky M. P. Ponomarenko D. A. Afonnikov |
| author_facet | D. A. Rasskazov K. V. Gunbin P. M. Ponomarenko O. V. Vishnevsky M. P. Ponomarenko D. A. Afonnikov |
| author_sort | D. A. Rasskazov |
| collection | DOAJ |
| description | Web-service SNP_TATA_Comparator has been developed for using experimentally proven in silico evaluation of in vivo biochemical manifestations of SNPs in the core promoter regions of human genes associated with diseases on the base of the TBP/TATA complex equilibrium equation (TBP is TATA binding protein). Data of individual deviations from the reference human genome (Ensembl, rel. 68, i.e. the variant of human genome commonly accepted as datum in comparison analysis) are accessible for free in the real-time mode. Also, data from the GENCODE database (rel. 17) are automatically invoked. The reported Web service SNP_TATA_Comparator is designed for personalized medicine using individual genomes in diagnosis, monitoring, prevention, and treatment. |
| format | Article |
| id | doaj-art-fe41d60ac5da41399153e19adf1135b4 |
| institution | Kabale University |
| issn | 2500-3259 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders |
| record_format | Article |
| series | Вавиловский журнал генетики и селекции |
| spelling | doaj-art-fe41d60ac5da41399153e19adf1135b42025-02-01T09:58:00ZengSiberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and BreedersВавиловский журнал генетики и селекции2500-32592015-01-01174/1599606167SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEXD. A. Rasskazov0K. V. Gunbin1P. M. Ponomarenko2O. V. Vishnevsky3M. P. Ponomarenko4D. A. Afonnikov5Institute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk National Research State University, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, RussiaInstitute of Cytology and Genetics SB RAS, Novosibirsk, Russia Novosibirsk National Research State University, Novosibirsk, RussiaWeb-service SNP_TATA_Comparator has been developed for using experimentally proven in silico evaluation of in vivo biochemical manifestations of SNPs in the core promoter regions of human genes associated with diseases on the base of the TBP/TATA complex equilibrium equation (TBP is TATA binding protein). Data of individual deviations from the reference human genome (Ensembl, rel. 68, i.e. the variant of human genome commonly accepted as datum in comparison analysis) are accessible for free in the real-time mode. Also, data from the GENCODE database (rel. 17) are automatically invoked. The reported Web service SNP_TATA_Comparator is designed for personalized medicine using individual genomes in diagnosis, monitoring, prevention, and treatment.https://vavilov.elpub.ru/jour/article/view/183snpтата boxтврgene expressionhuman diseases |
| spellingShingle | D. A. Rasskazov K. V. Gunbin P. M. Ponomarenko O. V. Vishnevsky M. P. Ponomarenko D. A. Afonnikov SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEX Вавиловский журнал генетики и селекции snp тата box твр gene expression human diseases |
| title | SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEX |
| title_full | SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEX |
| title_fullStr | SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEX |
| title_full_unstemmed | SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEX |
| title_short | SNP_TATA_COMPARATOR: Web SERVICE FOR COMPARISON OF SNPs WITHIN GENE PROMOTЕRS ASSOCIATED WITH HUMAN DISEASES USING THE EQUILIBRIUM EQUATION OF THE TBP/TATA COMPLEX |
| title_sort | snp tata comparator web service for comparison of snps within gene promotеrs associated with human diseases using the equilibrium equation of the tbp tata complex |
| topic | snp тата box твр gene expression human diseases |
| url | https://vavilov.elpub.ru/jour/article/view/183 |
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