Evaluation of the etiological spectrum of obstructive jaundice in patients attending the Al-Azhar Assiut University Hospital Endoscopy Unit in the last five years
Background and aim The term ‘cholestasis’ refers to a condition in which the bile flow is reduced, either because of decreased secretion by hepatocytes or because of intrahepatic or extrahepatic bile duct blockage. This study is intended to evaluate the Etiological Spectrum of Obstructive Jaundice i...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-04-01
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| Series: | Al-Azhar Assiut Medical Journal |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/azmj.azmj_1_23 |
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| Summary: | Background and aim
The term ‘cholestasis’ refers to a condition in which the bile flow is reduced, either because of decreased secretion by hepatocytes or because of intrahepatic or extrahepatic bile duct blockage.
This study is intended to evaluate the Etiological Spectrum of Obstructive Jaundice in Patients attending the Al-Azhar Assiut University Hospital Endoscopy Unit in the last 5 years.
Patients and methods
Our study was a retrospective study in which we reviewed ERCP records from January 2017 to January 2022 to detect the etiology of biliary obstruction. The ERCP procedure was performed in the Endoscopy Unit of Al-Azhar Assiut University Hospital.
Results
Twenty patients (3.1%) had shrunken liver, splenomegaly, and calcular gall bladder suggesting that calcular obstructive jaundice could occur on top of liver cirrhosis. Abdominal US was diagnostic for the cause of obstruction in 400 patients (62.5%). We also found that patients who had hepatic focal lesions, abdominal lymphadenopathy, and/or dilated biliary channels without obvious stones or masses in the abdominal US needed to be re-evaluated with MSCT abdomen with contrast imaging (240 cases, 37.5%).
Conclusion
Although abdominal, multislice, computed tomography fills the gap in diagnosing biliary strictures, it is still far behind magnetic resonance cholangiopancreatography for revealing biliary pancreatic masses. Endoscopic retrograde cholangiopancreatography is highly effective for treating biliary blockage; in case of failure, we resort to either surgery or percutaneous transhepatic drainage. |
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| ISSN: | 1687-1693 |