Prolonged versus single dose in penicillin oral challenge testing: protocols for a pilot and definitive randomised controlled trial (PROSPECTOR studies)

Prolonged versus single dose in penicillin oral challenge testing: protocols for a pilot and definitive randomised controlled trial (PROSPECTOR studies)

Introduction Penicillin allergy labels (PALs) are reported in 1 in 10 hospitalised patients globally and associated with inferior patient, hospital and microbiological outcomes; however, the majority are incorrect and should be removed. Direct oral penicillin challenge has been demonstrated to be a...

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Main Authors: Vito Sabato, Jason Trubiano, Sara Vogrin, Richard Sullivan, Michael Lane, Suran Fernando, Fiona James, Jonathan Grant Peter, Morgan Rose, Amy Legg, Irvin Ng, Ana Copaescu, Elise Mitri, Jack Godsell, Lene Heise Garvey, Philip Li
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/2/e094712.full
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