Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve
Background Currently, there is a lack of evidence for the long‐term bioprosthetic valve durability of patients with bicuspid aortic valve (BAV) following transcatheter aortic valve replacement (TAVR). Methods and Results This study aimed to evaluate hemodynamic outcome, structural valve deterioratio...
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Wiley
2024-11-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
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| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.035772 |
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| author | Hong‐De Li Wei‐Ya Li Jun‐Li Li Shi‐Qin Peng Yuan Feng Yong Peng Jia‐Fu Wei Zhen‐Gang Zhao Tian‐Yuan Xiong Yuan‐Wei Xiang Ou Yan Wang Qing Li Hao‐Ran Yang Cheng‐Xiang Song Yi‐Jun Yao Zhong‐Kai Zhu Qi Liu Xi Wang Mao Chen |
| author_facet | Hong‐De Li Wei‐Ya Li Jun‐Li Li Shi‐Qin Peng Yuan Feng Yong Peng Jia‐Fu Wei Zhen‐Gang Zhao Tian‐Yuan Xiong Yuan‐Wei Xiang Ou Yan Wang Qing Li Hao‐Ran Yang Cheng‐Xiang Song Yi‐Jun Yao Zhong‐Kai Zhu Qi Liu Xi Wang Mao Chen |
| author_sort | Hong‐De Li |
| collection | DOAJ |
| description | Background Currently, there is a lack of evidence for the long‐term bioprosthetic valve durability of patients with bicuspid aortic valve (BAV) following transcatheter aortic valve replacement (TAVR). Methods and Results This study aimed to evaluate hemodynamic outcome, structural valve deterioration, and bioprosthetic valve failure during long‐term follow‐up after TAVR in patients with BAV versus patients with tricuspid aortic valve (TAV). Patients with BAV and TAV who underwent TAVR between 2012 and 2020, with echocardiography followed for at least 3 years, were included. Baseline characteristics, long‐term valve hemodynamic performance, structural valve deterioration, and bioprosthetic valve failure were compared between patients with BAV and TAV. A total of 170 patients with BAV and 145 patients with TAV were included. The mean duration of follow‐up for patients with BAV and TAV was 5.2±1.8 and 5.0±1.7 years. No significant differences were observed in the rates of structural valve deterioration and bioprosthetic valve failure between patients with BAV and TAV: structural valve deterioration, BAV 20 (11.8%) versus TAV 16 (11.0%) at last follow‐up (P=0.861); bioprosthetic valve failure, BAV 3 (1.8%) versus TAV 7 (4.8%) at last follow‐up (P=0.196). More than moderate intravalvular aortic regurgitation (1.8% versus 4.8%, P=0.196) and paravalvular leak (6.5% versus 3.4%, P=0.305) were rare in both patients with BAV and patients with TAV. Conclusions This study indicated satisfactory long‐term valve durability of TAVR in patients with BAV. Comparable hemodynamic outcome, structural valve deterioration, and bioprosthetic valve failure could be achieved in patients with BAV and TAV during long‐term follow‐up after TAVR. |
| format | Article |
| id | doaj-art-fe27ddc7832d42c09d79f29b5c09dc49 |
| institution | DOAJ |
| issn | 2047-9980 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj-art-fe27ddc7832d42c09d79f29b5c09dc492025-08-20T02:48:57ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802024-11-01132110.1161/JAHA.124.035772Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic ValveHong‐De Li0Wei‐Ya Li1Jun‐Li Li2Shi‐Qin Peng3Yuan Feng4Yong Peng5Jia‐Fu Wei6Zhen‐Gang Zhao7Tian‐Yuan Xiong8Yuan‐Wei Xiang Ou9Yan Wang10Qing Li11Hao‐Ran Yang12Cheng‐Xiang Song13Yi‐Jun Yao14Zhong‐Kai Zhu15Qi Liu16Xi Wang17Mao Chen18Department of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaLaboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaLaboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaDepartment of Cardiology West China Hospital, Sichuan University Chengdu People’s Republic of ChinaBackground Currently, there is a lack of evidence for the long‐term bioprosthetic valve durability of patients with bicuspid aortic valve (BAV) following transcatheter aortic valve replacement (TAVR). Methods and Results This study aimed to evaluate hemodynamic outcome, structural valve deterioration, and bioprosthetic valve failure during long‐term follow‐up after TAVR in patients with BAV versus patients with tricuspid aortic valve (TAV). Patients with BAV and TAV who underwent TAVR between 2012 and 2020, with echocardiography followed for at least 3 years, were included. Baseline characteristics, long‐term valve hemodynamic performance, structural valve deterioration, and bioprosthetic valve failure were compared between patients with BAV and TAV. A total of 170 patients with BAV and 145 patients with TAV were included. The mean duration of follow‐up for patients with BAV and TAV was 5.2±1.8 and 5.0±1.7 years. No significant differences were observed in the rates of structural valve deterioration and bioprosthetic valve failure between patients with BAV and TAV: structural valve deterioration, BAV 20 (11.8%) versus TAV 16 (11.0%) at last follow‐up (P=0.861); bioprosthetic valve failure, BAV 3 (1.8%) versus TAV 7 (4.8%) at last follow‐up (P=0.196). More than moderate intravalvular aortic regurgitation (1.8% versus 4.8%, P=0.196) and paravalvular leak (6.5% versus 3.4%, P=0.305) were rare in both patients with BAV and patients with TAV. Conclusions This study indicated satisfactory long‐term valve durability of TAVR in patients with BAV. Comparable hemodynamic outcome, structural valve deterioration, and bioprosthetic valve failure could be achieved in patients with BAV and TAV during long‐term follow‐up after TAVR.https://www.ahajournals.org/doi/10.1161/JAHA.124.035772bicuspid aortic valvestructural valve degenerationtranscatheter aortic valve replacementvalve durability |
| spellingShingle | Hong‐De Li Wei‐Ya Li Jun‐Li Li Shi‐Qin Peng Yuan Feng Yong Peng Jia‐Fu Wei Zhen‐Gang Zhao Tian‐Yuan Xiong Yuan‐Wei Xiang Ou Yan Wang Qing Li Hao‐Ran Yang Cheng‐Xiang Song Yi‐Jun Yao Zhong‐Kai Zhu Qi Liu Xi Wang Mao Chen Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease bicuspid aortic valve structural valve degeneration transcatheter aortic valve replacement valve durability |
| title | Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve |
| title_full | Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve |
| title_fullStr | Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve |
| title_full_unstemmed | Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve |
| title_short | Long‐Term Durability of Transcatheter Aortic Valve Prostheses in Patients With Bicuspid Versus Tricuspid Aortic Valve |
| title_sort | long term durability of transcatheter aortic valve prostheses in patients with bicuspid versus tricuspid aortic valve |
| topic | bicuspid aortic valve structural valve degeneration transcatheter aortic valve replacement valve durability |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.124.035772 |
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