Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study

Introduction Hip fractures have several adverse effects on patients’ morbidity and mortality. Postoperative Acute kidney injury (AKI) is one of the complications that have a significant impact on the patient’s overall prognosis. We aimed to identify AKI risk after hip fracture surgery and the preope...

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Main Authors: Bassem I. Haddad, Abdulrahman A. Alhajahjeh, Abdelrahman Altarazi, Layla El-Amayreh, Mohammad Hamdan, Batool AlQuabeh, Waid Abd Ul Ghani, Randa I. Farah
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
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Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2023.2223313
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author Bassem I. Haddad
Abdulrahman A. Alhajahjeh
Abdelrahman Altarazi
Layla El-Amayreh
Mohammad Hamdan
Batool AlQuabeh
Waid Abd Ul Ghani
Randa I. Farah
author_facet Bassem I. Haddad
Abdulrahman A. Alhajahjeh
Abdelrahman Altarazi
Layla El-Amayreh
Mohammad Hamdan
Batool AlQuabeh
Waid Abd Ul Ghani
Randa I. Farah
author_sort Bassem I. Haddad
collection DOAJ
description Introduction Hip fractures have several adverse effects on patients’ morbidity and mortality. Postoperative Acute kidney injury (AKI) is one of the complications that have a significant impact on the patient’s overall prognosis. We aimed to identify AKI risk after hip fracture surgery and the preoperative and intraoperative risk factors.Methodology We conducted a retrospective cohort study in a tertiary care hospital on adult patients who underwent surgery for hip fractures between January 2015 and August 2021. All clinical data were reviewed.Result A total of 611 patients were included (age = 76.44 ± 9.69 years). 126 (20.6%) of them developed AKI postoperatively. In multilinear logistic regression analysis, factors associated with postoperative AKI included eGFR [odds ratio (OR): 0.98; 95% confidence interval (CI): 0.97–0.99 with a p value .01], spinal anesthesia [OR: 1.78; 95% CI: 1.1–2.9 with a p value .01], and partial hip replacement (PHR) type of surgery [OR: 0.56; 95% CI: 0.32–0.96 with a p value .036]. The development of postoperative AKI was the strongest factor that increase mortality of the patients as the (HR = 2.42, CI 95% [1.57–3.74]; p value <.001).Conclusion In this study, we highlight that lower eGFR, and spinal anesthesia were associated with a higher risk of AKI, and PHR surgery has lower odds to develop AKI. Postoperative AKI is associated with a higher mortality rate after hip fracture surgery.
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spelling doaj-art-fe253600d7424ec2b51cd64f806f8d8f2025-08-20T02:28:46ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492023-12-0145110.1080/0886022X.2023.2223313Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective studyBassem I. Haddad0Abdulrahman A. Alhajahjeh1Abdelrahman Altarazi2Layla El-Amayreh3Mohammad Hamdan4Batool AlQuabeh5Waid Abd Ul Ghani6Randa I. Farah7Department of Special Surgery, Division of Orthopedics, School of Medicine, The University of Jordan, Amman, JordanFaculty of Medicine, The University of Jordan, Amman, JordanDepartment of Special Surgery, Division of Orthopedics, School of Medicine, The University of Jordan, Amman, JordanFaculty of Medicine, The University of Jordan, Amman, JordanDepartment of Special Surgery, Division of Orthopedics, School of Medicine, The University of Jordan, Amman, JordanFaculty of Medicine, The University of Jordan, Amman, JordanFaculty of Medicine, The University of Jordan, Amman, JordanAffiliation Nephrology Division, Internal Medicine Department, School of Medicine, The University of Jordan, Amman, JordanIntroduction Hip fractures have several adverse effects on patients’ morbidity and mortality. Postoperative Acute kidney injury (AKI) is one of the complications that have a significant impact on the patient’s overall prognosis. We aimed to identify AKI risk after hip fracture surgery and the preoperative and intraoperative risk factors.Methodology We conducted a retrospective cohort study in a tertiary care hospital on adult patients who underwent surgery for hip fractures between January 2015 and August 2021. All clinical data were reviewed.Result A total of 611 patients were included (age = 76.44 ± 9.69 years). 126 (20.6%) of them developed AKI postoperatively. In multilinear logistic regression analysis, factors associated with postoperative AKI included eGFR [odds ratio (OR): 0.98; 95% confidence interval (CI): 0.97–0.99 with a p value .01], spinal anesthesia [OR: 1.78; 95% CI: 1.1–2.9 with a p value .01], and partial hip replacement (PHR) type of surgery [OR: 0.56; 95% CI: 0.32–0.96 with a p value .036]. The development of postoperative AKI was the strongest factor that increase mortality of the patients as the (HR = 2.42, CI 95% [1.57–3.74]; p value <.001).Conclusion In this study, we highlight that lower eGFR, and spinal anesthesia were associated with a higher risk of AKI, and PHR surgery has lower odds to develop AKI. Postoperative AKI is associated with a higher mortality rate after hip fracture surgery.https://www.tandfonline.com/doi/10.1080/0886022X.2023.2223313Hip fractureorthopedic surgeryacute kidney injurypreoperativerisk factorsretrospective cohort study
spellingShingle Bassem I. Haddad
Abdulrahman A. Alhajahjeh
Abdelrahman Altarazi
Layla El-Amayreh
Mohammad Hamdan
Batool AlQuabeh
Waid Abd Ul Ghani
Randa I. Farah
Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study
Renal Failure
Hip fracture
orthopedic surgery
acute kidney injury
preoperative
risk factors
retrospective cohort study
title Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study
title_full Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study
title_fullStr Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study
title_full_unstemmed Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study
title_short Preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery: a cohort retrospective study
title_sort preoperative and intraoperative risk factors for acute kidney injury after hip fracture surgery a cohort retrospective study
topic Hip fracture
orthopedic surgery
acute kidney injury
preoperative
risk factors
retrospective cohort study
url https://www.tandfonline.com/doi/10.1080/0886022X.2023.2223313
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