Programming megakaryocytes to produce engineered platelets for delivering non-native proteins
Abstract Platelets are anucleate cells naturally filled with secretory granules that store large amounts of protein to be released in response to certain physiological conditions. Cell engineering can endow platelets with the ability to deliver non-native proteins by modifying them as they develop d...
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| Main Authors: | Farhana Islam, Shwan B. Javdan, Mitchell R. Lewis, James D. Craig, Han Wu, Tara L. Deans |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08017-8 |
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