PD-1/PD-L1 and coronary heart disease: a mendelian randomization study

PD-1/PD-L1 and coronary heart disease: a mendelian randomization study

IntroductionIt has been found that programmed cell death protein-1 (PD-1) or its ligand PD-L1 may play an important role in the onset and progression of coronary heart disease (CHD). Thus, we conducted this mendelian randomization analysis (MR) to estimate the causal relationship between PD-1/PD-L1...

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Bibliographic Details
Main Authors: Liangjia Zeng, Yinglan Liang, Ruoyun Zhou, Wenting Yang, Kexin Chen, Baixin He, Yuqing Qiu, Linglong Liu, Deyang Zhou, Zhaolin Xiao, Haowen Liang, Binghua Zhang, Renyu Li, Lihong Yu, Min Yi, Xiaozhen Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Mendelian randomization (MR)
coronary heart disease (CHD)
PD-1
PD-L1
GSEA
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1424770/full
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