Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case Report

Varicella-zoster virus (VZV) is transmitted through airborne respiratory secretions, initially causing chickenpox. After the primary infection, the virus establishes latency within the dorsal sensory ganglia and may later reactivate, resulting in a vesicular dermatomal eruption known as herpes zoste...

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Main Author: Ali Alkarawi
Format: Article
Language:English
Published: University of Kirkuk, College of Medicine, Kirkuk, Iraq 2025-04-01
Series:Kirkuk Journal of Medical Sciences
Subjects:
Online Access:https://kjms.uokirkuk.edu.iq/article_186883_90f9753600b0ee9d3e55d0380042ac45.pdf
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author Ali Alkarawi
author_facet Ali Alkarawi
author_sort Ali Alkarawi
collection DOAJ
description Varicella-zoster virus (VZV) is transmitted through airborne respiratory secretions, initially causing chickenpox. After the primary infection, the virus establishes latency within the dorsal sensory ganglia and may later reactivate, resulting in a vesicular dermatomal eruption known as herpes zoster (HZ). The simultaneous occurrence of herpes zoster first and chickenpox later in susceptible individuals is an exceedingly rare phenomenon and is considered an unprecedented event that necessitates further exploration.This report presents a case of an 11-year-old girl diagnosed with herpes zoster ophthalmicus (HZO), affecting the ophthalmic division of the right trigeminal nerve. Three days later, she developed chickenpox. The patient’s mother had a documented history of varicella infection during her 32 weeks of gestation. An intriguing aspect of this case is the simultaneous infection of the patient’s younger sister, who resided in the same household and also contracted chickenpox at the same time. Early initiation of antiviral and anticonvulsant therapy effectively mitigated the severity of HZ symptoms, while the varicella manifestations in both siblings remained mild, necessitating only symptomatic management with antipruritic lotion. The zoster lesions required approximately six weeks for complete resolution, leaving behind substantial scarring on the forehead, eyelid edema, and scarring alopecia at the affected site.
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spelling doaj-art-fe192d3183f046b5bce3dc92a2c4707c2025-08-20T02:53:53ZengUniversity of Kirkuk, College of Medicine, Kirkuk, IraqKirkuk Journal of Medical Sciences2790-02072790-02152025-04-01131667010.32894/kjms.2025.155296.1135186883Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case ReportAli Alkarawi0Department of Dermatology, Azadi Teaching Hospital, Kiruk Health Directorate, Kirkuk, IRAQ.Varicella-zoster virus (VZV) is transmitted through airborne respiratory secretions, initially causing chickenpox. After the primary infection, the virus establishes latency within the dorsal sensory ganglia and may later reactivate, resulting in a vesicular dermatomal eruption known as herpes zoster (HZ). The simultaneous occurrence of herpes zoster first and chickenpox later in susceptible individuals is an exceedingly rare phenomenon and is considered an unprecedented event that necessitates further exploration.This report presents a case of an 11-year-old girl diagnosed with herpes zoster ophthalmicus (HZO), affecting the ophthalmic division of the right trigeminal nerve. Three days later, she developed chickenpox. The patient’s mother had a documented history of varicella infection during her 32 weeks of gestation. An intriguing aspect of this case is the simultaneous infection of the patient’s younger sister, who resided in the same household and also contracted chickenpox at the same time. Early initiation of antiviral and anticonvulsant therapy effectively mitigated the severity of HZ symptoms, while the varicella manifestations in both siblings remained mild, necessitating only symptomatic management with antipruritic lotion. The zoster lesions required approximately six weeks for complete resolution, leaving behind substantial scarring on the forehead, eyelid edema, and scarring alopecia at the affected site.https://kjms.uokirkuk.edu.iq/article_186883_90f9753600b0ee9d3e55d0380042ac45.pdfherpes zoster ophthalmicuschickenpoxvaricella during pregnancy
spellingShingle Ali Alkarawi
Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case Report
Kirkuk Journal of Medical Sciences
herpes zoster ophthalmicus
chickenpox
varicella during pregnancy
title Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case Report
title_full Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case Report
title_fullStr Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case Report
title_full_unstemmed Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case Report
title_short Simultaneous Onset of Herpes Zoster Ophthalmicus and Chickenpox in the Context of Maternal Varicella; A Rare Case Report
title_sort simultaneous onset of herpes zoster ophthalmicus and chickenpox in the context of maternal varicella a rare case report
topic herpes zoster ophthalmicus
chickenpox
varicella during pregnancy
url https://kjms.uokirkuk.edu.iq/article_186883_90f9753600b0ee9d3e55d0380042ac45.pdf
work_keys_str_mv AT alialkarawi simultaneousonsetofherpeszosterophthalmicusandchickenpoxinthecontextofmaternalvaricellaararecasereport