Anti-cariogenic activity of mutanocyclin, a secondary metabolite of Streptococcus mutans, in mono- and multispecies biofilms

Anti-cariogenic activity of mutanocyclin, a secondary metabolite of Streptococcus mutans, in mono- and multispecies biofilms

ABSTRACT Streptococcus mutans (S. mutans), a principal cariogenic pathogen responsible for dental caries, alters the oral biofilm ecology through the production of various metabolites. One such metabolite, mutanocyclin (MUC), a recently identified secondary metabolite, may have implications for both...

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Bibliographic Details
Main Authors: Fangting Huang, Yang Zhou, Dongru Chen, Huancai Lin
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
mutanocyclin
Streptococcus mutans
Streptococcus gordonii
Streptococcus sanguinis
multispecies biofilms
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00183-25
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