Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds
The implantation of bone substitutes depends on the material’s osteoconductive potential and the structure’s porosity Porosity is a characteristic feature of most materials. The porosity of materials has a strong influence on some of their properties, both structural and functional. An essential req...
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| Language: | English |
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Sumy State University
2021-06-01
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| Series: | Журнал інженерних наук |
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| Online Access: | http://jes.sumdu.edu.ua/wp-content/uploads/2021/07/jes_8_1_2021_C18-C28.pdf |
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| author | Chernobrovchenko V. S. Dyadyura K. О. Balynskyi M. Panda A. |
| author_facet | Chernobrovchenko V. S. Dyadyura K. О. Balynskyi M. Panda A. |
| author_sort | Chernobrovchenko V. S. |
| collection | DOAJ |
| description | The implantation of bone substitutes depends on the material’s osteoconductive potential and the structure’s porosity Porosity is a characteristic feature of most materials. The porosity of materials has a strong influence on some of their properties, both structural and functional. An essential requirement for bone scaffolds is porosity, which guides cells into their physical structure and supports vascularization. The macroporosity should be large enough and interdependent for bone ingrowth to occur throughout the entire volume of the implant. The pore size for cell colonization in bioceramics is approximately 100 μm. Pores larger than this value promote bone growth through the material. This pore size allows the flow of growth factors and cell adhesion and proliferation, allowing the formation of new bone and developing the capillary system associated with the ceramic implant. Porosity also affects the rate of resorption of ceramics: the larger the number of micropores, the higher the dissolution rate. The investigated properties were elastic moduli, ultimate strength, compressive strength, and average apparent density. The results obtained in this work are consistent with previous studies, proving the positive role of microporosity in osseointegration and bone formation. |
| format | Article |
| id | doaj-art-fe0dd48248b74b3b895918007b6d139a |
| institution | OA Journals |
| issn | 2312-2498 2414-9381 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Sumy State University |
| record_format | Article |
| series | Журнал інженерних наук |
| spelling | doaj-art-fe0dd48248b74b3b895918007b6d139a2025-08-20T02:15:54ZengSumy State UniversityЖурнал інженерних наук2312-24982414-93812021-06-0181C18C2810.21272/jes.2021.8(1).c3Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffoldsChernobrovchenko V. S.0Dyadyura K. О.1Balynskyi M.2Panda A.3Sumy State University, 2, Rymskogo-Korsakova St., 40007, Sumy, UkraineSumy State University, 2, Rymskogo-Korsakova St., 40007, Sumy, UkraineSumy State University, 2, Rymskogo-Korsakova St., 40007, Sumy, UkraineFaculty of Manufacturing Technologies with a seat in Prešov, Technical University of Košice, 080 01, Prešov, SlovakiaThe implantation of bone substitutes depends on the material’s osteoconductive potential and the structure’s porosity Porosity is a characteristic feature of most materials. The porosity of materials has a strong influence on some of their properties, both structural and functional. An essential requirement for bone scaffolds is porosity, which guides cells into their physical structure and supports vascularization. The macroporosity should be large enough and interdependent for bone ingrowth to occur throughout the entire volume of the implant. The pore size for cell colonization in bioceramics is approximately 100 μm. Pores larger than this value promote bone growth through the material. This pore size allows the flow of growth factors and cell adhesion and proliferation, allowing the formation of new bone and developing the capillary system associated with the ceramic implant. Porosity also affects the rate of resorption of ceramics: the larger the number of micropores, the higher the dissolution rate. The investigated properties were elastic moduli, ultimate strength, compressive strength, and average apparent density. The results obtained in this work are consistent with previous studies, proving the positive role of microporosity in osseointegration and bone formation.http://jes.sumdu.edu.ua/wp-content/uploads/2021/07/jes_8_1_2021_C18-C28.pdfporosityporosity influencehydroxyapatitebone substituterelationshiposseointegration |
| spellingShingle | Chernobrovchenko V. S. Dyadyura K. О. Balynskyi M. Panda A. Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds Журнал інженерних наук porosity porosity influence hydroxyapatite bone substitute relationship osseointegration |
| title | Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds |
| title_full | Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds |
| title_fullStr | Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds |
| title_full_unstemmed | Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds |
| title_short | Influence of technological manufacturing conditions on the porosity of calcium-phosphate scaffolds |
| title_sort | influence of technological manufacturing conditions on the porosity of calcium phosphate scaffolds |
| topic | porosity porosity influence hydroxyapatite bone substitute relationship osseointegration |
| url | http://jes.sumdu.edu.ua/wp-content/uploads/2021/07/jes_8_1_2021_C18-C28.pdf |
| work_keys_str_mv | AT chernobrovchenkovs influenceoftechnologicalmanufacturingconditionsontheporosityofcalciumphosphatescaffolds AT dyadyurako influenceoftechnologicalmanufacturingconditionsontheporosityofcalciumphosphatescaffolds AT balynskyim influenceoftechnologicalmanufacturingconditionsontheporosityofcalciumphosphatescaffolds AT pandaa influenceoftechnologicalmanufacturingconditionsontheporosityofcalciumphosphatescaffolds |