The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 Diabetes
Background. It has been well accepted that insulin therapy is the ideal treatment for newly diagnosed diabetic patients. However, there was no study about assessment of the initial insulin dosage in new onset Chinese patients with type 2 diabetes. Research Design and Methods. 65 newly diagnosed pa...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2016/7245947 |
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| author | Jing Ma Huan Zhou Hua Xu Xie Chen Xiangyu Teng Qianjing Liu Wei Liu |
| author_facet | Jing Ma Huan Zhou Hua Xu Xie Chen Xiangyu Teng Qianjing Liu Wei Liu |
| author_sort | Jing Ma |
| collection | DOAJ |
| description | Background. It has been well accepted that insulin therapy is the ideal treatment for newly diagnosed diabetic patients. However, there was no study about assessment of the initial insulin dosage in new onset Chinese patients with type 2 diabetes. Research Design and Methods. 65 newly diagnosed patients with type 2 diabetes (39 males/26 females; HbA1c ≥ 11.80 ± 0.22%) were investigated. All patients had random hyperglycaemia (at 21.8 ± 3.9 mmol/L) on the first day of admission and received insulin infusion intravenously (5 U/per hour). When the blood glucose level dropped to around 10 mmol/L, patients were then transferred to continuous subcutaneous insulin infusion (CSII). The reduction of blood glucose levels in response to per unit of insulin (RBG/RI) was recorded. The target glucose level was achieved in about 3 days. The total daily insulin dose (TDD) and basal insulin dose (TBD) were calculated. Results. TDD was 45.97 ± 1.28 units and TBD was 19.00 ± 0.54 units. TBD was about 40% of the total daily insulin requirement. There was a negative correlation between the ratio of RBG/RI and TDD. Conclusions. TDD was correlated with blood glucose reduction in response to intravenous insulin infusion in Chinese new onset patients with type 2 diabetes. |
| format | Article |
| id | doaj-art-fe0769ab8554483987907ca36827983c |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-fe0769ab8554483987907ca36827983c2025-02-03T01:02:05ZengWileyJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/72459477245947The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 DiabetesJing Ma0Huan Zhou1Hua Xu2Xie Chen3Xiangyu Teng4Qianjing Liu5Wei Liu6Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, ChinaDepartment of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630 Dongfang Road, Shanghai 200127, ChinaBackground. It has been well accepted that insulin therapy is the ideal treatment for newly diagnosed diabetic patients. However, there was no study about assessment of the initial insulin dosage in new onset Chinese patients with type 2 diabetes. Research Design and Methods. 65 newly diagnosed patients with type 2 diabetes (39 males/26 females; HbA1c ≥ 11.80 ± 0.22%) were investigated. All patients had random hyperglycaemia (at 21.8 ± 3.9 mmol/L) on the first day of admission and received insulin infusion intravenously (5 U/per hour). When the blood glucose level dropped to around 10 mmol/L, patients were then transferred to continuous subcutaneous insulin infusion (CSII). The reduction of blood glucose levels in response to per unit of insulin (RBG/RI) was recorded. The target glucose level was achieved in about 3 days. The total daily insulin dose (TDD) and basal insulin dose (TBD) were calculated. Results. TDD was 45.97 ± 1.28 units and TBD was 19.00 ± 0.54 units. TBD was about 40% of the total daily insulin requirement. There was a negative correlation between the ratio of RBG/RI and TDD. Conclusions. TDD was correlated with blood glucose reduction in response to intravenous insulin infusion in Chinese new onset patients with type 2 diabetes.http://dx.doi.org/10.1155/2016/7245947 |
| spellingShingle | Jing Ma Huan Zhou Hua Xu Xie Chen Xiangyu Teng Qianjing Liu Wei Liu The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 Diabetes Journal of Diabetes Research |
| title | The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 Diabetes |
| title_full | The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 Diabetes |
| title_fullStr | The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 Diabetes |
| title_full_unstemmed | The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 Diabetes |
| title_short | The Initial Assessment of Daily Insulin Dose in Chinese Newly Diagnosed Type 2 Diabetes |
| title_sort | initial assessment of daily insulin dose in chinese newly diagnosed type 2 diabetes |
| url | http://dx.doi.org/10.1155/2016/7245947 |
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