Protocol for implementing the nested model for AI design and validation in compliance with AI regulations

Summary: Here, we present a protocol for implementing the nested model for developing and validating artificial intelligence (AI) systems in compliance with AI regulations. We describe steps for defining the regulations and associated ethical and technical key requirements through the potential rese...

Full description

Saved in:
Bibliographic Details
Main Authors: Akshat Dubey, Zewen Yang, Aleksandar Anžel, Georges Hattab
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166725001777
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849729941257584640
author Akshat Dubey
Zewen Yang
Aleksandar Anžel
Georges Hattab
author_facet Akshat Dubey
Zewen Yang
Aleksandar Anžel
Georges Hattab
author_sort Akshat Dubey
collection DOAJ
description Summary: Here, we present a protocol for implementing the nested model for developing and validating artificial intelligence (AI) systems in compliance with AI regulations. We describe steps for defining the regulations and associated ethical and technical key requirements through the potential research questions. We then detail the procedures for designing and validating an AI application across the domain, data, model, and prediction layers, enabling users to interact with layers through a front-end interface.For complete information on the generation and use of this protocol, please refer to Dubey et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.
format Article
id doaj-art-fdf71c037ab64073a4e245cfb63eda91
institution DOAJ
issn 2666-1667
language English
publishDate 2025-06-01
publisher Elsevier
record_format Article
series STAR Protocols
spelling doaj-art-fdf71c037ab64073a4e245cfb63eda912025-08-20T03:09:01ZengElsevierSTAR Protocols2666-16672025-06-016210377110.1016/j.xpro.2025.103771Protocol for implementing the nested model for AI design and validation in compliance with AI regulationsAkshat Dubey0Zewen Yang1Aleksandar Anžel2Georges Hattab3Center for Artificial Intelligence in the Public Health Research (ZKI-PH) at Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany; Department of Mathematics and Computer Science, Freie Universität Berlin, Arnimallee 14, 14195 Berlin, Germany; Corresponding authorCenter for Artificial Intelligence in the Public Health Research (ZKI-PH) at Robert Koch Institute, Nordufer 20, 13353 Berlin, GermanyCenter for Artificial Intelligence in the Public Health Research (ZKI-PH) at Robert Koch Institute, Nordufer 20, 13353 Berlin, GermanyCenter for Artificial Intelligence in the Public Health Research (ZKI-PH) at Robert Koch Institute, Nordufer 20, 13353 Berlin, Germany; Department of Mathematics and Computer Science, Freie Universität Berlin, Arnimallee 14, 14195 Berlin, GermanySummary: Here, we present a protocol for implementing the nested model for developing and validating artificial intelligence (AI) systems in compliance with AI regulations. We describe steps for defining the regulations and associated ethical and technical key requirements through the potential research questions. We then detail the procedures for designing and validating an AI application across the domain, data, model, and prediction layers, enabling users to interact with layers through a front-end interface.For complete information on the generation and use of this protocol, please refer to Dubey et al.1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.http://www.sciencedirect.com/science/article/pii/S2666166725001777Health SciencesComputer sciences
spellingShingle Akshat Dubey
Zewen Yang
Aleksandar Anžel
Georges Hattab
Protocol for implementing the nested model for AI design and validation in compliance with AI regulations
STAR Protocols
Health Sciences
Computer sciences
title Protocol for implementing the nested model for AI design and validation in compliance with AI regulations
title_full Protocol for implementing the nested model for AI design and validation in compliance with AI regulations
title_fullStr Protocol for implementing the nested model for AI design and validation in compliance with AI regulations
title_full_unstemmed Protocol for implementing the nested model for AI design and validation in compliance with AI regulations
title_short Protocol for implementing the nested model for AI design and validation in compliance with AI regulations
title_sort protocol for implementing the nested model for ai design and validation in compliance with ai regulations
topic Health Sciences
Computer sciences
url http://www.sciencedirect.com/science/article/pii/S2666166725001777
work_keys_str_mv AT akshatdubey protocolforimplementingthenestedmodelforaidesignandvalidationincompliancewithairegulations
AT zewenyang protocolforimplementingthenestedmodelforaidesignandvalidationincompliancewithairegulations
AT aleksandaranzel protocolforimplementingthenestedmodelforaidesignandvalidationincompliancewithairegulations
AT georgeshattab protocolforimplementingthenestedmodelforaidesignandvalidationincompliancewithairegulations