Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation
ABSTRACT Pesticides play a crucial role in safeguarding crops against pathogens and pests, yet the limited bioavailability of conventional formulations leads to excessive usage, causing environmental and health concerns. In this study, we developed a novel intelligent response‐controlled release nan...
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2024-12-01
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| Series: | Modern Agriculture |
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| Online Access: | https://doi.org/10.1002/moda.70001 |
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| author | Ruixin Li Xiaochen Jia Hongguo Xie Xueran Wang Jinxuan Wen Guanglu Yu Chunlai Zhang Yeqing Sun Heng Yin |
| author_facet | Ruixin Li Xiaochen Jia Hongguo Xie Xueran Wang Jinxuan Wen Guanglu Yu Chunlai Zhang Yeqing Sun Heng Yin |
| author_sort | Ruixin Li |
| collection | DOAJ |
| description | ABSTRACT Pesticides play a crucial role in safeguarding crops against pathogens and pests, yet the limited bioavailability of conventional formulations leads to excessive usage, causing environmental and health concerns. In this study, we developed a novel intelligent response‐controlled release nano‐pesticide, Vali@mPEG‐TK‐COS, by coupling chitosan oligosaccharide (COS), a plant immunity regulator, and methoxy polyethylene glycols (mPEG) at either end of thioketal (TK), a material responsive to reactive oxygen species (ROS), and incorporating validamycin (Vali) for controlled release. Vali@mPEG‐TK‐COS exhibits ROS‐responsive behaviour, releasing Vali and COS in response to plant ROS bursts, exhibiting dual capabilities in pathogen control and plant immunity induction during pathogenic attacks. Plant disease experiments confirmed the superior efficacy of Vali@mPEG‐TK‐COS against Rhizoctonia solani, surpassing the control effects of Vali or COS alone. This study presents a sophisticated ROS‐responsive controlled‐release nano‐pesticide with dual fungicidal and plant immunomodulatory properties, offering an advanced strategy to enhance the efficiency of existing pesticides and promote sustainable crop production by reducing overall pesticide usage. |
| format | Article |
| id | doaj-art-fddf8882c94d4ce883bdcafbcac35d74 |
| institution | Kabale University |
| issn | 2751-4102 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Modern Agriculture |
| spelling | doaj-art-fddf8882c94d4ce883bdcafbcac35d742025-01-31T16:15:28ZengWiley-VCHModern Agriculture2751-41022024-12-0122n/an/a10.1002/moda.70001Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune ModulationRuixin Li0Xiaochen Jia1Hongguo Xie2Xueran Wang3Jinxuan Wen4Guanglu Yu5Chunlai Zhang6Yeqing Sun7Heng Yin8Dalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaDalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaDalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaDalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaDalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaDalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaDalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaInstitute of Environmental Systems Biology Dalian Maritime University Dalian ChinaDalian Engineering Research Center for Carbohydrate Agricultural Preparations Dalian Technology Innovation Center for Green Agriculture Liaoning Provincial Key Laboratory of Carbohydrates Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian ChinaABSTRACT Pesticides play a crucial role in safeguarding crops against pathogens and pests, yet the limited bioavailability of conventional formulations leads to excessive usage, causing environmental and health concerns. In this study, we developed a novel intelligent response‐controlled release nano‐pesticide, Vali@mPEG‐TK‐COS, by coupling chitosan oligosaccharide (COS), a plant immunity regulator, and methoxy polyethylene glycols (mPEG) at either end of thioketal (TK), a material responsive to reactive oxygen species (ROS), and incorporating validamycin (Vali) for controlled release. Vali@mPEG‐TK‐COS exhibits ROS‐responsive behaviour, releasing Vali and COS in response to plant ROS bursts, exhibiting dual capabilities in pathogen control and plant immunity induction during pathogenic attacks. Plant disease experiments confirmed the superior efficacy of Vali@mPEG‐TK‐COS against Rhizoctonia solani, surpassing the control effects of Vali or COS alone. This study presents a sophisticated ROS‐responsive controlled‐release nano‐pesticide with dual fungicidal and plant immunomodulatory properties, offering an advanced strategy to enhance the efficiency of existing pesticides and promote sustainable crop production by reducing overall pesticide usage.https://doi.org/10.1002/moda.70001bifunctional nano‐pesticideschitosan oligosaccharidefungicideimmunomodulatoryRhizoctonia solani |
| spellingShingle | Ruixin Li Xiaochen Jia Hongguo Xie Xueran Wang Jinxuan Wen Guanglu Yu Chunlai Zhang Yeqing Sun Heng Yin Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation Modern Agriculture bifunctional nano‐pesticides chitosan oligosaccharide fungicide immunomodulatory Rhizoctonia solani |
| title | Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation |
| title_full | Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation |
| title_fullStr | Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation |
| title_full_unstemmed | Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation |
| title_short | Vali@mPEG‐TK‐COS: A Dual‐Function Nano‐Pesticide for Fungicidal Action and Plant Immune Modulation |
| title_sort | vali mpeg tk cos a dual function nano pesticide for fungicidal action and plant immune modulation |
| topic | bifunctional nano‐pesticides chitosan oligosaccharide fungicide immunomodulatory Rhizoctonia solani |
| url | https://doi.org/10.1002/moda.70001 |
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