Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo Surabaya

Background and objectives. Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction causing fluctuating skeletal muscle weakness and fatigue that result in increased restrictions on physical activity, affecting the patient's ability to perform daily activities in the family...

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Main Authors: Iin Muslihah, RA Meisy Andriana, Yudith Dian Prawitri, Paulus Sugianto, Soenarnatalina Melaniani
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2024-09-01
Series:Romanian Journal of Neurology
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Online Access:https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-12.pdf
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author Iin Muslihah
RA Meisy Andriana
Yudith Dian Prawitri
Paulus Sugianto
Soenarnatalina Melaniani
author_facet Iin Muslihah
RA Meisy Andriana
Yudith Dian Prawitri
Paulus Sugianto
Soenarnatalina Melaniani
author_sort Iin Muslihah
collection DOAJ
description Background and objectives. Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction causing fluctuating skeletal muscle weakness and fatigue that result in increased restrictions on physical activity, affecting the patient's ability to perform daily activities in the family, social, and work environment. The MG-ADL scale is an assessment of the ability of the daily activities of MG patients that does not require equipment or special skills for the examiner and can be done in a short time. This study analyzes the effect of low intensity aerobic exercise cycle ergometer on the ability to perform daily activities of MG patients. Materials and methods. Twenty-two MG patients, MGFA class IIa and IIb, aged 18–59, participated in this study. The subjects were randomly divided into a treatment group and a control group. The treatment group received aerobic cycle ergometer exercise for 30 minutes, three times per week, for eight weeks. Both groups were educated to continue medication from neurology, perform physical activity as usual, and breathing exercises. Assessment of MG-ADL performed before and after intervention. Results. There was an improvement in scores on breathing and lower limb function in the treatment group. There was significant decrease in MG-ADL scores at the intervention group (p = 0.000) with large effect size (1.09). The comparison of MG-ADL scores between groups showed a significant value (p = 0.009) with a large effect size (1.24). Conclusion. Low intensity aerobic exercise cycle ergometer for 8 weeks improves the ability to perform ADL in MG patient.
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spelling doaj-art-fdd786e596ed41b881f9af35d0d11d752025-08-20T01:59:01ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942024-09-0123330431010.37897/RJN.2024.3.12Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo SurabayaIin Muslihah0https://orcid.org/0009-0002-5951-4877RA Meisy Andriana1Yudith Dian Prawitri2Paulus Sugianto3Soenarnatalina Melaniani4Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Physical Medicine and Rehabilitation, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Neuromuscular Rehabilitation Division, Department of Physical Medicine and Rehabilitation, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Neuromuscular Rehabilitation Division, Department of Physical Medicine and Rehabilitation, Airlangga University Hospital, Surabaya, Indonesia Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Intensive and Neurocritical Division, Department of Neurology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Department of Epidemiology, Biostatistics, Population Studies and Health Promotion, Faculty of Public Health, Universitas Airlangga, Surabaya, IndonesiaBackground and objectives. Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction causing fluctuating skeletal muscle weakness and fatigue that result in increased restrictions on physical activity, affecting the patient's ability to perform daily activities in the family, social, and work environment. The MG-ADL scale is an assessment of the ability of the daily activities of MG patients that does not require equipment or special skills for the examiner and can be done in a short time. This study analyzes the effect of low intensity aerobic exercise cycle ergometer on the ability to perform daily activities of MG patients. Materials and methods. Twenty-two MG patients, MGFA class IIa and IIb, aged 18–59, participated in this study. The subjects were randomly divided into a treatment group and a control group. The treatment group received aerobic cycle ergometer exercise for 30 minutes, three times per week, for eight weeks. Both groups were educated to continue medication from neurology, perform physical activity as usual, and breathing exercises. Assessment of MG-ADL performed before and after intervention. Results. There was an improvement in scores on breathing and lower limb function in the treatment group. There was significant decrease in MG-ADL scores at the intervention group (p = 0.000) with large effect size (1.09). The comparison of MG-ADL scores between groups showed a significant value (p = 0.009) with a large effect size (1.24). Conclusion. Low intensity aerobic exercise cycle ergometer for 8 weeks improves the ability to perform ADL in MG patient.https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-12.pdfcycle ergometermyasthenia gravisactivity of daily livingneuromuscular disease
spellingShingle Iin Muslihah
RA Meisy Andriana
Yudith Dian Prawitri
Paulus Sugianto
Soenarnatalina Melaniani
Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo Surabaya
Romanian Journal of Neurology
cycle ergometer
myasthenia gravis
activity of daily living
neuromuscular disease
title Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo Surabaya
title_full Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo Surabaya
title_fullStr Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo Surabaya
title_full_unstemmed Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo Surabaya
title_short Effect of low-intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in RSUD Dr. Soetomo Surabaya
title_sort effect of low intensity aerobic cycling ergometer on ability to perform activity of daily living of patients with myasthenia gravis in rsud dr soetomo surabaya
topic cycle ergometer
myasthenia gravis
activity of daily living
neuromuscular disease
url https://rjn.com.ro/articles/2024.3/RJN_2024_3_Art-12.pdf
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