Enterocytozoon bieneusi, a human pathogen

Although brought to the forefront in the 1980s with the AIDS pandemic, microsporidia infecting humans are still little known. Enterocytozoon bieneusi, by far the most frequent microsporidia species causing diseases in humans, is responsible for intestinal illness in both non- and immunocompromised p...

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Main Authors: Céline Nourrisson, Rose-Anne Lavergne, Maxime Moniot, Florent Morio, Philippe Poirier
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
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Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2406276
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author Céline Nourrisson
Rose-Anne Lavergne
Maxime Moniot
Florent Morio
Philippe Poirier
author_facet Céline Nourrisson
Rose-Anne Lavergne
Maxime Moniot
Florent Morio
Philippe Poirier
author_sort Céline Nourrisson
collection DOAJ
description Although brought to the forefront in the 1980s with the AIDS pandemic, microsporidia infecting humans are still little known. Enterocytozoon bieneusi, by far the most frequent microsporidia species causing diseases in humans, is responsible for intestinal illness in both non- and immunocompromised patients. This species presents an astonishing genetic diversity with more than 500 genotypes described, some of which have a strong zoonotic potential. Indeed, E. bieneusi infects a broad array of hosts, from wild to domestic animals. This emerging eukaryotic pathogen has thus been associated with foodborne/waterborne outbreaks. Several molecular assays have been developed to enhance its diagnosis or for epidemiological purposes, providing valuable new data. Here, we propose an overview of the current knowledge on this major species among the microsporidia, so far rather neglected in human medicine.
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series Emerging Microbes and Infections
spelling doaj-art-fdcb30b8ed7d4ae6b56bca1b522ab1962025-08-20T01:55:19ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512024-12-0113110.1080/22221751.2024.2406276Enterocytozoon bieneusi, a human pathogenCéline Nourrisson0Rose-Anne Lavergne1Maxime Moniot2Florent Morio3Philippe Poirier4Parasitology & Mycology unit, 3IHP, University Hospital of Clermont-Ferrand, Clermont-Ferrand, FranceNantes Université, CHU Nantes, Cibles et Médicaments des Infections et de l'Immunité, Nantes, FranceParasitology & Mycology unit, 3IHP, University Hospital of Clermont-Ferrand, Clermont-Ferrand, FranceNantes Université, CHU Nantes, Cibles et Médicaments des Infections et de l'Immunité, Nantes, FranceParasitology & Mycology unit, 3IHP, University Hospital of Clermont-Ferrand, Clermont-Ferrand, FranceAlthough brought to the forefront in the 1980s with the AIDS pandemic, microsporidia infecting humans are still little known. Enterocytozoon bieneusi, by far the most frequent microsporidia species causing diseases in humans, is responsible for intestinal illness in both non- and immunocompromised patients. This species presents an astonishing genetic diversity with more than 500 genotypes described, some of which have a strong zoonotic potential. Indeed, E. bieneusi infects a broad array of hosts, from wild to domestic animals. This emerging eukaryotic pathogen has thus been associated with foodborne/waterborne outbreaks. Several molecular assays have been developed to enhance its diagnosis or for epidemiological purposes, providing valuable new data. Here, we propose an overview of the current knowledge on this major species among the microsporidia, so far rather neglected in human medicine.https://www.tandfonline.com/doi/10.1080/22221751.2024.2406276Enterocytozoon bieneusimicrosporidiaopportunistic infectious diseasesintestinal pathogenfoodborne pathogenwaterborne pathogen
spellingShingle Céline Nourrisson
Rose-Anne Lavergne
Maxime Moniot
Florent Morio
Philippe Poirier
Enterocytozoon bieneusi, a human pathogen
Emerging Microbes and Infections
Enterocytozoon bieneusi
microsporidia
opportunistic infectious diseases
intestinal pathogen
foodborne pathogen
waterborne pathogen
title Enterocytozoon bieneusi, a human pathogen
title_full Enterocytozoon bieneusi, a human pathogen
title_fullStr Enterocytozoon bieneusi, a human pathogen
title_full_unstemmed Enterocytozoon bieneusi, a human pathogen
title_short Enterocytozoon bieneusi, a human pathogen
title_sort enterocytozoon bieneusi a human pathogen
topic Enterocytozoon bieneusi
microsporidia
opportunistic infectious diseases
intestinal pathogen
foodborne pathogen
waterborne pathogen
url https://www.tandfonline.com/doi/10.1080/22221751.2024.2406276
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AT roseannelavergne enterocytozoonbieneusiahumanpathogen
AT maximemoniot enterocytozoonbieneusiahumanpathogen
AT florentmorio enterocytozoonbieneusiahumanpathogen
AT philippepoirier enterocytozoonbieneusiahumanpathogen