The effect of preoperative vaginal preparation with povidone-iodine on post-caesarean section infection
Objective: To evaluate the effect of preoperative vaginal antiseptic cleansing with Povidone-iodine on the occurrence of post-caesarean section infectious morbidity. Methodology: A single-blind randomized controlled study of 180 women who had preoperative vaginal preparation with povidone-iodine...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Babcock Medical Society
2024-12-01
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| Series: | Babcock University Medical Journal |
| Subjects: | |
| Online Access: | http://bumj.babcock.edu.ng/index.php/bumj/article/view/506 |
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| Summary: | Objective: To evaluate the effect of preoperative vaginal antiseptic cleansing with Povidone-iodine on the occurrence of post-caesarean section infectious morbidity.
Methodology: A single-blind randomized controlled study of 180 women who had preoperative vaginal preparation with povidone-iodine before emergency CS at the University of Ilorin teaching hospital during the study period, The primary outcome measures were fever, endometritis and wound infection. Analysis was done using Chi-square tests, t-tests and logistic regression.
Results: The study result shows that the prevalence of post-caesarean section infection morbidity was 26.5%. There was a statistically significant difference in educational level attained and social class (p<0.001) between both groups. The incidence of post-caesarean infection was significantly lower among the subjects compared to the controls (16.3% vs.36.6%,p-0.003). Using univariate and multivariate binary logistic regression, PVP-I use and chorioamnionitis remain significant independent predictors of infectious morbidity. PVP-I is associated with lesser odds (OR; 0.307) while those with chorioamnionitis are eight times more likely to have a postoperative infection (p-0.006).
Conclusion: The incidence of post-caesarean fever and endometritis was significantly reduced in those scrubbed with both abdominal and vaginal Povidone-iodine compared to those who had standard abdominal scrub alone for emergency caesarean section. Vaginal cleaning with Povidone-iodine is safe.
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| ISSN: | 2465-6666 2756-4657 |