A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province

ObjectiveTo investigate the impact of healthy lifestyles on all-cause and cardiovascular disease (CVD) mortality among adult residents in Guizhou province, and to provide a reference for reducing mortality risk in the local population. MethodsA prospective cohort study was conducted using a multi-st...

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Main Authors: Jie ZHOU, Ling LI, Ji ZHANG, Lisha YU, Yujin REN, Wei JI, Yingjiao MU, Tao LIU
Format: Article
Language:zho
Published: Editorial Office of Chinese Journal of Public Health 2024-12-01
Series:Zhongguo gonggong weisheng
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Online Access:https://www.zgggws.com/article/doi/10.11847/zgggws1145088
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author Jie ZHOU
Ling LI
Ji ZHANG
Lisha YU
Yujin REN
Wei JI
Yingjiao MU
Tao LIU
author_facet Jie ZHOU
Ling LI
Ji ZHANG
Lisha YU
Yujin REN
Wei JI
Yingjiao MU
Tao LIU
author_sort Jie ZHOU
collection DOAJ
description ObjectiveTo investigate the impact of healthy lifestyles on all-cause and cardiovascular disease (CVD) mortality among adult residents in Guizhou province, and to provide a reference for reducing mortality risk in the local population. MethodsA prospective cohort study was conducted using a multi-stage cluster random sampling method to recruit 9 280 permanent residents aged ≥ 18 years in Guizhou province from November 2010 to December 2012 for a baseline survey. Two follow-up surveys were conducted in December 2016 to June 2020 and December 2023, respectively. After excluding participants with incomplete baseline lifestyle information and loss to follow-up, 9 085 adult residents were finally included. A multivariable Cox proportional hazards regression model was used to analyze the impact of healthy lifestyles on all-cause and CVD mortality among adult residents in Guizhou province. ResultsThe 9 085 adult residents in Guizhou province were followed up for 0.10 – 13.07 years, with an average follow-up of (11.73 ± 1.49) years. During the follow-up period, there were 594 all-cause deaths and 241 CVD deaths, with mortality rates of 6.5% and 2.7%, and mortality densities of 5.57/1 000 person-years and 2.26/1 000 person-years, respectively. Among the 9 085 adult residents in Guizhou province, 545 (6.0%), 1 841 (20.3%), 3 064 (33.7%), 2 419 (26.6%), and 1 216 (13.4%) had ≤ 3, 4, 5, 6, and ≥ 7 healthy lifestyle factors, respectively. The all-cause mortality densities during follow-up were 10.38/1 000 person-years, 6.74/1 000 person-years, 5.38/1 000 person-years, 4.82/1 000 person-years, and 3.69/1 000 person-years, respectively, and the CVD mortality densities were 4.31/1 000 person-years, 2.79/1 000 person-years, 2.25/1 000 person-years, 2.00/1 000 person-years, and 1.11/1 000 person-years, respectively. After adjusting for confounding factors such as sex, age, ethnicity, education level, marital status, residence, systolic blood pressure, diastolic blood pressure, fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG), total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), the multivariable Cox proportional hazards regression analysis showed that the risks of all-cause mortality among adult residents in Guizhou province with 4, 5, 6, and ≥ 7 healthy lifestyle factors were 0.732 times (HR = 0.732, 95%CI: 0.542 – 0.990), 0.667 times (HR = 0.667, 95%CI: 0.499 – 0.893), 0.664 times (HR = 0.664, 95%CI: 0.490 – 0.900), and 0.566 times (HR = 0.566, 95%CI: 0.391 – 0.820) that of those with ≤ 3 healthy lifestyle factors, respectively. The risk of CVD mortality among adult residents in Guizhou province with ≥ 7 healthy lifestyle factors was 0.444 times (HR = 0.444, 95%CI: 0.236 – 0.833) that of those with ≤ 3 healthy lifestyle factors. ConclusionsThe more healthy lifestyle factors adopted by adult residents in Guizhou province, the lower their risks of all-cause and CVD mortality.
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spelling doaj-art-fdc6016f306c496e9e81b006f93b85692025-02-11T02:11:59ZzhoEditorial Office of Chinese Journal of Public HealthZhongguo gonggong weisheng1001-05802024-12-0140121440144510.11847/zgggws11450881145088A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou provinceJie ZHOU0Ling LI1Ji ZHANG2Lisha YU3Yujin REN4Wei JI5Yingjiao MU6Tao LIU7Guizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaGuizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaGuizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaGuizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaGuizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaGuizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaGuizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaGuizhou Center for Disease Control and Prevention, Guiyang 550000, ChinaObjectiveTo investigate the impact of healthy lifestyles on all-cause and cardiovascular disease (CVD) mortality among adult residents in Guizhou province, and to provide a reference for reducing mortality risk in the local population. MethodsA prospective cohort study was conducted using a multi-stage cluster random sampling method to recruit 9 280 permanent residents aged ≥ 18 years in Guizhou province from November 2010 to December 2012 for a baseline survey. Two follow-up surveys were conducted in December 2016 to June 2020 and December 2023, respectively. After excluding participants with incomplete baseline lifestyle information and loss to follow-up, 9 085 adult residents were finally included. A multivariable Cox proportional hazards regression model was used to analyze the impact of healthy lifestyles on all-cause and CVD mortality among adult residents in Guizhou province. ResultsThe 9 085 adult residents in Guizhou province were followed up for 0.10 – 13.07 years, with an average follow-up of (11.73 ± 1.49) years. During the follow-up period, there were 594 all-cause deaths and 241 CVD deaths, with mortality rates of 6.5% and 2.7%, and mortality densities of 5.57/1 000 person-years and 2.26/1 000 person-years, respectively. Among the 9 085 adult residents in Guizhou province, 545 (6.0%), 1 841 (20.3%), 3 064 (33.7%), 2 419 (26.6%), and 1 216 (13.4%) had ≤ 3, 4, 5, 6, and ≥ 7 healthy lifestyle factors, respectively. The all-cause mortality densities during follow-up were 10.38/1 000 person-years, 6.74/1 000 person-years, 5.38/1 000 person-years, 4.82/1 000 person-years, and 3.69/1 000 person-years, respectively, and the CVD mortality densities were 4.31/1 000 person-years, 2.79/1 000 person-years, 2.25/1 000 person-years, 2.00/1 000 person-years, and 1.11/1 000 person-years, respectively. After adjusting for confounding factors such as sex, age, ethnicity, education level, marital status, residence, systolic blood pressure, diastolic blood pressure, fasting blood glucose (FBG), 2-hour postprandial blood glucose (PBG), total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C), the multivariable Cox proportional hazards regression analysis showed that the risks of all-cause mortality among adult residents in Guizhou province with 4, 5, 6, and ≥ 7 healthy lifestyle factors were 0.732 times (HR = 0.732, 95%CI: 0.542 – 0.990), 0.667 times (HR = 0.667, 95%CI: 0.499 – 0.893), 0.664 times (HR = 0.664, 95%CI: 0.490 – 0.900), and 0.566 times (HR = 0.566, 95%CI: 0.391 – 0.820) that of those with ≤ 3 healthy lifestyle factors, respectively. The risk of CVD mortality among adult residents in Guizhou province with ≥ 7 healthy lifestyle factors was 0.444 times (HR = 0.444, 95%CI: 0.236 – 0.833) that of those with ≤ 3 healthy lifestyle factors. ConclusionsThe more healthy lifestyle factors adopted by adult residents in Guizhou province, the lower their risks of all-cause and CVD mortality.https://www.zgggws.com/article/doi/10.11847/zgggws1145088healthy lifestyleall-cause mortalitycardiovascular disease (cvd) mortalityimpactadult residentsprospective cohort studyguizhou province
spellingShingle Jie ZHOU
Ling LI
Ji ZHANG
Lisha YU
Yujin REN
Wei JI
Yingjiao MU
Tao LIU
A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province
Zhongguo gonggong weisheng
healthy lifestyle
all-cause mortality
cardiovascular disease (cvd) mortality
impact
adult residents
prospective cohort study
guizhou province
title A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province
title_full A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province
title_fullStr A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province
title_full_unstemmed A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province
title_short A prospective cohort study on the impact of healthy lifestyles on all-cause and cardiovascular disease mortality among adult residents in Guizhou province
title_sort prospective cohort study on the impact of healthy lifestyles on all cause and cardiovascular disease mortality among adult residents in guizhou province
topic healthy lifestyle
all-cause mortality
cardiovascular disease (cvd) mortality
impact
adult residents
prospective cohort study
guizhou province
url https://www.zgggws.com/article/doi/10.11847/zgggws1145088
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