Retroviral foamy virus gag induces parkin-dependent mitophagy

Retroviral foamy virus gag induces parkin-dependent mitophagy

Abstract Background Prototype foamy virus (PFV) is a complex retrovirus that can maintain latent infection for life after viral infection of the host. However, the mechanism of latent infection with PFV remains unclear. Our previous studies have shown that PFV promotes autophagy flux, but whether PF...

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Main Authors: Shanshan Wang, Tongtong Du, Jun Yan, Yingcheng Zheng, Yinglian Tang, Juejie Wu, Qian Xu, Shanshan Xu, Luo Liu, Xiong Chen, Song Han, Jun Yin, Biwen Peng, Xiaohua He, Wanhong Liu
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Retrovirology
Subjects:
Prototype foamy virus
Gag
Mitophagy
Parkin
Rab5a
Online Access:https://doi.org/10.1186/s12977-025-00664-3
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