Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A review

Background: Orthodontic treatment with fixed appliances is frequently associated with difficulties in maintaining good oral hygiene and creation of plaque-retentive areas on tooth surfaces that are typically more prone to the development of caries; such drawbacks may result in white spot lesion (WS...

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Main Authors: Dana R Mohammed, Ali I Ibrahim, Sanjukta Deb
Format: Article
Language:English
Published: College of Dentistry/ University of Baghdad 2025-06-01
Series:Journal of Baghdad College of Dentistry
Subjects:
Online Access:https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3970
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author Dana R Mohammed
Ali I Ibrahim
Sanjukta Deb
author_facet Dana R Mohammed
Ali I Ibrahim
Sanjukta Deb
author_sort Dana R Mohammed
collection DOAJ
description Background: Orthodontic treatment with fixed appliances is frequently associated with difficulties in maintaining good oral hygiene and creation of plaque-retentive areas on tooth surfaces that are typically more prone to the development of caries; such drawbacks may result in white spot lesion (WSL) development that affects the esthetic outcome following bracket debonding. This review article focuses on orthodontic WSLs development, prevention, and remineralization potential via incorporating various remineralizing / antibacterial additives into orthodontic adhesives. Results: Unbalanced enamel demineralization and remineralization processes, along with rapid alterations in the dental plaque bacterial ecology, particularly acidogenic bacteria, are the causes of the start and progression of a carious lesion. Without significantly compromising an adhesive mechanical performance, several antibacterial and remineralizing substances have been added to orthodontic adhesives in an effort to reduce bacterial colonization and promote remineralization. Conclusions: Antibacterial and/or remineralizing substances were utilized as additives in the creation of innovative orthodontic adhesive systems to address white spot lesions (WSLs) and improve the ability of enamel remineralization. Compared to adding only one agent, including multiple agents in an orthodontic adhesive system may have a greater impact on lowering enamel demineralization and improving enamel remineralization during orthodontic therapy.
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publishDate 2025-06-01
publisher College of Dentistry/ University of Baghdad
record_format Article
series Journal of Baghdad College of Dentistry
spelling doaj-art-fdb467eeaf2b445ebf9f5830dc342b292025-08-20T03:46:49ZengCollege of Dentistry/ University of BaghdadJournal of Baghdad College of Dentistry1817-18692311-52702025-06-0137210.26477/jbcd.v37i2.3970Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A reviewDana R Mohammed0https://orcid.org/0000-0001-8299-048XAli I Ibrahim1https://orcid.org/0000-0002-8476-3034Sanjukta Deb2https://orcid.org/0000-0001-5000-4390College of Dentistry, University of Baghdad, Baghdad, Iraq; Department of P.O.P., College of Dentistry, University of Basrah, Basrah, IraqCollege of Dentistry, University of Baghdad, Baghdad, Iraq; Centre for Oral Clinical and Translational Sciences, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, UKCentre for Oral Clinical and Translational Sciences, Faculty of Dentistry, Oral and Craniofacial Sciences, King’s College London, London, UK Background: Orthodontic treatment with fixed appliances is frequently associated with difficulties in maintaining good oral hygiene and creation of plaque-retentive areas on tooth surfaces that are typically more prone to the development of caries; such drawbacks may result in white spot lesion (WSL) development that affects the esthetic outcome following bracket debonding. This review article focuses on orthodontic WSLs development, prevention, and remineralization potential via incorporating various remineralizing / antibacterial additives into orthodontic adhesives. Results: Unbalanced enamel demineralization and remineralization processes, along with rapid alterations in the dental plaque bacterial ecology, particularly acidogenic bacteria, are the causes of the start and progression of a carious lesion. Without significantly compromising an adhesive mechanical performance, several antibacterial and remineralizing substances have been added to orthodontic adhesives in an effort to reduce bacterial colonization and promote remineralization. Conclusions: Antibacterial and/or remineralizing substances were utilized as additives in the creation of innovative orthodontic adhesive systems to address white spot lesions (WSLs) and improve the ability of enamel remineralization. Compared to adding only one agent, including multiple agents in an orthodontic adhesive system may have a greater impact on lowering enamel demineralization and improving enamel remineralization during orthodontic therapy. https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3970white spot lesionenamel remineralizationorthodontic adhesivebracket bondingantibacterial agents
spellingShingle Dana R Mohammed
Ali I Ibrahim
Sanjukta Deb
Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A review
Journal of Baghdad College of Dentistry
white spot lesion
enamel remineralization
orthodontic adhesive
bracket bonding
antibacterial agents
title Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A review
title_full Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A review
title_fullStr Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A review
title_full_unstemmed Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A review
title_short Combating white spot lesions via incorporation of remineralizing/ antibacterial additives into orthodontic adhesives: A review
title_sort combating white spot lesions via incorporation of remineralizing antibacterial additives into orthodontic adhesives a review
topic white spot lesion
enamel remineralization
orthodontic adhesive
bracket bonding
antibacterial agents
url https://www.jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/3970
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AT aliiibrahim combatingwhitespotlesionsviaincorporationofremineralizingantibacterialadditivesintoorthodonticadhesivesareview
AT sanjuktadeb combatingwhitespotlesionsviaincorporationofremineralizingantibacterialadditivesintoorthodonticadhesivesareview