Prognostic value of FLOT1-related gene signature in head and neck squamous cell carcinoma: insights into radioresistance mechanisms and clinical outcomes

Prognostic value of FLOT1-related gene signature in head and neck squamous cell carcinoma: insights into radioresistance mechanisms and clinical outcomes

Abstract We aimed to develop and validate the ability of a FLOT1-related gene signature to predict survival in head and neck squamous cell carcinoma (HNSCC) patients and to explore FLOT1’s role in modulating the responses to radiation therapy (RT). Using TCGA dataset, we identified a gene expression...

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Main Authors: Min Kyeong Lee, Seon Rang Woo, Joo Kyung Noh, MinJi Bae, YeonSeo Lee, Soonki Min, Moonkyoo Kong, Young Chan Lee, Seong‐Gyu Ko, Young-Gyu Eun
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02500-1
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