PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMEN

The problem of infectious diseases during pregnancy continues to be relevant. It could be connected with possible complications during pregnancy and with the probability of the risk of intrauterine infection. One of the most common infections in the world, including among women of reproductive perio...

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Main Authors: N. Yu. Katkova, N. A. Kabatin, O. V. Kachalina
Format: Article
Language:Russian
Published: IRBIS LLC 2016-06-01
Series:Акушерство, гинекология и репродукция
Subjects:
Online Access:https://www.gynecology.su/jour/article/view/143
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author N. Yu. Katkova
N. A. Kabatin
O. V. Kachalina
author_facet N. Yu. Katkova
N. A. Kabatin
O. V. Kachalina
author_sort N. Yu. Katkova
collection DOAJ
description The problem of infectious diseases during pregnancy continues to be relevant. It could be connected with possible complications during pregnancy and with the probability of the risk of intrauterine infection. One of the most common infections in the world, including among women of reproductive period is human papilloma virus (HPV) infection. There is lack of detailed information on risk factors for intrauterine fetal contagion with HPV infection. Objectives. Study objective was to reveal risk factors of vertical transfer of HPV. Materials and methods. 102 pregnant women with various forms of a papilloma virus infection are examined using real time polymerase chain reaction (PCR). Exclusion criteria were invasive and preinvasive cervical cancer, HIV infection, with concomitant CMV or HSV infection. Results. The general frequency of prenatal HPV infection was 14.7%. Risk factors of vertical transmission: high virus load, squamosus intraepitelial lession, abnormality vaginal biocenosis, reduction of secretory immunoglobulin in cervical mucus, increase in duration of vaginal birth and duration of the waterless period. There is not found correlation between age and social risk factors, parity, physical state and the frequency of HPV transmission from mother to child (p>0.05), as well as statistically significant impact on the incidence of fetal infection, complications of pregnancy and delivery method (p>0.05).
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spelling doaj-art-fdadc835407548d7be79b6d7268583352025-08-20T02:53:57ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-0191323710.17749/2313-7347.2015.9.1.032-037141PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMENN. Yu. Katkova0N. A. Kabatin1O. V. Kachalina2Nizhny Novgorod State Medical AcademyNizhny Novgorod State Medical AcademyNizhny Novgorod State Medical AcademyThe problem of infectious diseases during pregnancy continues to be relevant. It could be connected with possible complications during pregnancy and with the probability of the risk of intrauterine infection. One of the most common infections in the world, including among women of reproductive period is human papilloma virus (HPV) infection. There is lack of detailed information on risk factors for intrauterine fetal contagion with HPV infection. Objectives. Study objective was to reveal risk factors of vertical transfer of HPV. Materials and methods. 102 pregnant women with various forms of a papilloma virus infection are examined using real time polymerase chain reaction (PCR). Exclusion criteria were invasive and preinvasive cervical cancer, HIV infection, with concomitant CMV or HSV infection. Results. The general frequency of prenatal HPV infection was 14.7%. Risk factors of vertical transmission: high virus load, squamosus intraepitelial lession, abnormality vaginal biocenosis, reduction of secretory immunoglobulin in cervical mucus, increase in duration of vaginal birth and duration of the waterless period. There is not found correlation between age and social risk factors, parity, physical state and the frequency of HPV transmission from mother to child (p>0.05), as well as statistically significant impact on the incidence of fetal infection, complications of pregnancy and delivery method (p>0.05).https://www.gynecology.su/jour/article/view/143pregnancyhuman papillomavirus infectionhuman papilloma virusvertical transmission
spellingShingle N. Yu. Katkova
N. A. Kabatin
O. V. Kachalina
PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMEN
Акушерство, гинекология и репродукция
pregnancy
human papillomavirus infection
human papilloma virus
vertical transmission
title PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMEN
title_full PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMEN
title_fullStr PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMEN
title_full_unstemmed PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMEN
title_short PRENATAL INFECTION AT THE HUMAN PAPILLOMA VIRUS INFECTION AT PREGNANT WOMEN
title_sort prenatal infection at the human papilloma virus infection at pregnant women
topic pregnancy
human papillomavirus infection
human papilloma virus
vertical transmission
url https://www.gynecology.su/jour/article/view/143
work_keys_str_mv AT nyukatkova prenatalinfectionatthehumanpapillomavirusinfectionatpregnantwomen
AT nakabatin prenatalinfectionatthehumanpapillomavirusinfectionatpregnantwomen
AT ovkachalina prenatalinfectionatthehumanpapillomavirusinfectionatpregnantwomen