Homozygous mice with mutant protein FUS[1-359] overexpression: Innovative possibilities for ALS treatment
Introduction: This study investigates a mouse model with overexpression of the mutant FUS[1-359] protein, which can be used to evaluate the effectiveness of gene therapy and other pharmacological interventions for amyotrophic lateral sclerosis (ALS). The model enhances the deeper understanding of th...
Saved in:
| Main Author: | Nikita S. Zhunusov |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Belgorod National Research University
2024-12-01
|
| Series: | Research Results in Pharmacology |
| Subjects: | |
| Online Access: | https://rrpharmacology.ru/index.php/journal/article/view/554 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Case Report: A case of ALS type 6 associated with a FUS gene variant and right limb muscle weakness and atrophy as the initial symptom
by: Xiuping Zhan, et al.
Published: (2025-06-01) -
Overexpression of HSP70 in mice with mutant FUS protein is accompanied by a mitigated neurodegeneration in limbic system
by: G. A. Piavchenko, et al.
Published: (2025-05-01) -
A rare case of juvenile amyotrophic lateral sclerosis
by: Muhittin Bodur, et al.
Published: (2021-06-01) -
DOK7 gene therapy enhances motor activity and life span in ALS model mice
by: Sadanori Miyoshi, et al.
Published: (2017-05-01) -
Gene therapy breakthroughs in ALS: a beacon of hope for 20% of ALS patients
by: Qingjian Xie, et al.
Published: (2025-04-01)