Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer.

Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer.

Omics data integration is becoming necessary to investigate the genomic mechanisms involved in complex diseases. During the integration process, many challenges arise such as data heterogeneity, the smaller number of individuals in comparison to the number of parameters, multicollinearity, and inter...

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Main Authors: Silvia Pineda, Francisco X Real, Manolis Kogevinas, Alfredo Carrato, Stephen J Chanock, Núria Malats, Kristel Van Steen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1005689&type=printable
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