Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age

Aim. To analyze the results and features of early cardiac remodeling (CR) in children of preschool and school age after endovascular correction of atrial septal defect (ASD).Material and methods. A prospective study included 27 children with secondary ASD who underwent endovascular correction for on...

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Main Authors: R. S. Tarasov, P. A. Shushpannikov, V. I. Ganyukov, I. N. Sizova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2018-12-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/2960
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author R. S. Tarasov
P. A. Shushpannikov
V. I. Ganyukov
I. N. Sizova
author_facet R. S. Tarasov
P. A. Shushpannikov
V. I. Ganyukov
I. N. Sizova
author_sort R. S. Tarasov
collection DOAJ
description Aim. To analyze the results and features of early cardiac remodeling (CR) in children of preschool and school age after endovascular correction of atrial septal defect (ASD).Material and methods. A prospective study included 27 children with secondary ASD who underwent endovascular correction for one year (from the beginning of 2017 to the beginning of 2018). The patients were divided into two groups. The first (n=12) — children of preschool age (<8 years old), mean age 4,5 [3;6], and the second (n=15) — school age (8­18 years old), mean age 12 [9;14]. The following indicants were assessed during hospitalization: the success of the intervention, hospital complications, functional data characterizing CR according to echocardiography before and after the correction of the defect.Results. It was shown that all children successfully completed endovascular closure of ASD. Complications were not identified. We find several statistically significant changes in echocardiogram data before and after the intervention. In the preschool age group, the size of the right ventricle (RV) decreased from 1,66 to 1,45 cm (p=0,028), the right atrium (RA) decreased from 3,58 to 3,1 cm (p=0,003), and the longitudinal size of RV decreased from 3 to 2 cm (p=0,032) and basal size of RV — from 5,98 to 4,4 cm (p=0,005), the volume of RA decreased from 25,7 to 20,7 ml (p=0,005). In the group of school age, the size of the RV changed from 2,08 to 1,8 cm (p=0,038), the size of the RA — from 3,72 to 2,71 cm (p=0,007), the RV area in diastole — from 12,4 to 10,6 mm2. The gradient has changed from 2 to 1,54 mm Hg (p=0,043), the frontal size of the tricuspid valve (TV) decreased from 2,7 to 2,48 cm (p=0,010). The basal size of RV decreased from 3 to 2,6 cm (p=0,015), the median size — from 2,73 to 2,37 cm (p=0,017) and the longitudinal size — from 5,97 to 5,45 cm (p=0,007). No significant differences in CR among the groups were found.Conclusion. We made conclusion about the efficacy and safety of endovascular correction of ASD, which has a positive effect on early HR in children, both in early and in old age.
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spelling doaj-art-fd9a76208b014f2c81884edbcd6af9672025-08-20T03:57:26Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202018-12-01011273310.15829/1560-4071-2018-11-27-332496Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school ageR. S. Tarasov0P. A. Shushpannikov1V. I. Ganyukov2I. N. Sizova3Research Institute for Complex Issues of Cardiovascular Diseases.Research Institute for Complex Issues of Cardiovascular Diseases.Research Institute for Complex Issues of Cardiovascular Diseases.Research Institute for Complex Issues of Cardiovascular Diseases.Aim. To analyze the results and features of early cardiac remodeling (CR) in children of preschool and school age after endovascular correction of atrial septal defect (ASD).Material and methods. A prospective study included 27 children with secondary ASD who underwent endovascular correction for one year (from the beginning of 2017 to the beginning of 2018). The patients were divided into two groups. The first (n=12) — children of preschool age (<8 years old), mean age 4,5 [3;6], and the second (n=15) — school age (8­18 years old), mean age 12 [9;14]. The following indicants were assessed during hospitalization: the success of the intervention, hospital complications, functional data characterizing CR according to echocardiography before and after the correction of the defect.Results. It was shown that all children successfully completed endovascular closure of ASD. Complications were not identified. We find several statistically significant changes in echocardiogram data before and after the intervention. In the preschool age group, the size of the right ventricle (RV) decreased from 1,66 to 1,45 cm (p=0,028), the right atrium (RA) decreased from 3,58 to 3,1 cm (p=0,003), and the longitudinal size of RV decreased from 3 to 2 cm (p=0,032) and basal size of RV — from 5,98 to 4,4 cm (p=0,005), the volume of RA decreased from 25,7 to 20,7 ml (p=0,005). In the group of school age, the size of the RV changed from 2,08 to 1,8 cm (p=0,038), the size of the RA — from 3,72 to 2,71 cm (p=0,007), the RV area in diastole — from 12,4 to 10,6 mm2. The gradient has changed from 2 to 1,54 mm Hg (p=0,043), the frontal size of the tricuspid valve (TV) decreased from 2,7 to 2,48 cm (p=0,010). The basal size of RV decreased from 3 to 2,6 cm (p=0,015), the median size — from 2,73 to 2,37 cm (p=0,017) and the longitudinal size — from 5,97 to 5,45 cm (p=0,007). No significant differences in CR among the groups were found.Conclusion. We made conclusion about the efficacy and safety of endovascular correction of ASD, which has a positive effect on early HR in children, both in early and in old age.https://russjcardiol.elpub.ru/jour/article/view/2960congenital heart defectsatrial septal defectcardiac remodelingendovascular correction
spellingShingle R. S. Tarasov
P. A. Shushpannikov
V. I. Ganyukov
I. N. Sizova
Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age
Российский кардиологический журнал
congenital heart defects
atrial septal defect
cardiac remodeling
endovascular correction
title Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age
title_full Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age
title_fullStr Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age
title_full_unstemmed Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age
title_short Results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age
title_sort results of endovascular correction of atrial septal defect and early heart remodeling in children of preschool and school age
topic congenital heart defects
atrial septal defect
cardiac remodeling
endovascular correction
url https://russjcardiol.elpub.ru/jour/article/view/2960
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AT viganyukov resultsofendovascularcorrectionofatrialseptaldefectandearlyheartremodelinginchildrenofpreschoolandschoolage
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