Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)

Aim. To determine the role of cardio-ankle vascular index (CAVI) in predicting cardiovascular events (CVEs) in adult Russian population using model of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study (Tomsk).Material and methods. We...

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Main Authors: A. R. Zairova, A. N. Rogoza, E. V. Oshchepkova, E. B. Yarovaya, V. A. Kutsenko, S. A. Shalnova, I. A. Trubacheva, V. S. Kaveshnikov, V. N. Serebryakova, S. A. Boytcov
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2021-09-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/2967
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author A. R. Zairova
A. N. Rogoza
E. V. Oshchepkova
E. B. Yarovaya
V. A. Kutsenko
S. A. Shalnova
I. A. Trubacheva
V. S. Kaveshnikov
V. N. Serebryakova
S. A. Boytcov
author_facet A. R. Zairova
A. N. Rogoza
E. V. Oshchepkova
E. B. Yarovaya
V. A. Kutsenko
S. A. Shalnova
I. A. Trubacheva
V. S. Kaveshnikov
V. N. Serebryakova
S. A. Boytcov
author_sort A. R. Zairova
collection DOAJ
description Aim. To determine the role of cardio-ankle vascular index (CAVI) in predicting cardiovascular events (CVEs) in adult Russian population using model of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study (Tomsk).Material and methods. We analyzed the data of 1342 people aged 25-64 (4,3±11,6) years, in whom arterial stiffness was assessed as part of the ESSE-RF study using the vascular screening system VaSeraVS-1500, followed by phone contacts, on average, 4,7 years later. We studied the prognostic role of CAVI in relation to primary composite (cardiovascular death, nonfatal myocardial infarction (MI) or stroke) and secondary composite (all CVEs) endpoints.Results. We revealed that prior myocardial infarction or stroke (n=52) is associated with an increase in CVE incidence from 2,3 to 11,5% (p=0,0003) and from 5% to 23% (p<0,001) for primary and secondary composite endpoints, respectively. In a group of 1290 people (without prior MI or stroke), CAVI was significantly higher in men than in women: 7,4±1,4 vs 7,1±1,3 (p=0,002), despite more young age: 45,4±11,8 vs 48,0±11,3 years (p<0,001). The risk criterion for CVE was CAVI >7,8 (relative risk (RR): 5,06; 95% confidence interval (CI): 2,32-11,06) (p<0,001) and (RR: 3,95; 95% CI: 2,37-6,58) (p<0,001), which retains its predictive value when adjusted for conventional risk factors (RR: 3,13; 95% CI: 1,26-7,75) (p=0,014) and (RR: 2,16; 95% CI: 1,18-3,98) (p=0,013) — primary and secondary composite endpoints, respectively.Conclusion. CAVI has a significant independent value in predicting CVEs in Tomsk adult urban population aged 25-64 years. To clarify the cardiovascular risk, vascular screening with identifying CAVI should be carried out during preventive and screening examinations for men over 35 and women over 45.
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series Кардиоваскулярная терапия и профилактика
spelling doaj-art-fd98e6bb2eed464d92d618dab44b9fe42025-08-20T02:59:14Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252021-09-0120510.15829/1728-8800-2021-29672305Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)A. R. Zairova0A. N. Rogoza1E. V. Oshchepkova2E. B. Yarovaya3V. A. Kutsenko4S. A. Shalnova5I. A. Trubacheva6V. S. Kaveshnikov7V. N. Serebryakova8S. A. Boytcov9National Medical Research Center of CardiologyNational Medical Research Center of CardiologyNational Medical Research Center of CardiologyLomonosov Moscow State University; National Medical Research Center for Therapy and Preventive MedicineLomonosov Moscow State University; National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineCardiology Research Institute, Tomsk National Research Medical CenterCardiology Research Institute, Tomsk National Research Medical CenterCardiology Research Institute, Tomsk National Research Medical CenterNational Medical Research Center of CardiologyAim. To determine the role of cardio-ankle vascular index (CAVI) in predicting cardiovascular events (CVEs) in adult Russian population using model of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study (Tomsk).Material and methods. We analyzed the data of 1342 people aged 25-64 (4,3±11,6) years, in whom arterial stiffness was assessed as part of the ESSE-RF study using the vascular screening system VaSeraVS-1500, followed by phone contacts, on average, 4,7 years later. We studied the prognostic role of CAVI in relation to primary composite (cardiovascular death, nonfatal myocardial infarction (MI) or stroke) and secondary composite (all CVEs) endpoints.Results. We revealed that prior myocardial infarction or stroke (n=52) is associated with an increase in CVE incidence from 2,3 to 11,5% (p=0,0003) and from 5% to 23% (p<0,001) for primary and secondary composite endpoints, respectively. In a group of 1290 people (without prior MI or stroke), CAVI was significantly higher in men than in women: 7,4±1,4 vs 7,1±1,3 (p=0,002), despite more young age: 45,4±11,8 vs 48,0±11,3 years (p<0,001). The risk criterion for CVE was CAVI >7,8 (relative risk (RR): 5,06; 95% confidence interval (CI): 2,32-11,06) (p<0,001) and (RR: 3,95; 95% CI: 2,37-6,58) (p<0,001), which retains its predictive value when adjusted for conventional risk factors (RR: 3,13; 95% CI: 1,26-7,75) (p=0,014) and (RR: 2,16; 95% CI: 1,18-3,98) (p=0,013) — primary and secondary composite endpoints, respectively.Conclusion. CAVI has a significant independent value in predicting CVEs in Tomsk adult urban population aged 25-64 years. To clarify the cardiovascular risk, vascular screening with identifying CAVI should be carried out during preventive and screening examinations for men over 35 and women over 45.https://cardiovascular.elpub.ru/jour/article/view/2967esse-rfvolume sphygmographyarterial stiffnesscardioankle vascular index caviprognosiscardiovascular events
spellingShingle A. R. Zairova
A. N. Rogoza
E. V. Oshchepkova
E. B. Yarovaya
V. A. Kutsenko
S. A. Shalnova
I. A. Trubacheva
V. S. Kaveshnikov
V. N. Serebryakova
S. A. Boytcov
Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)
Кардиоваскулярная терапия и профилактика
esse-rf
volume sphygmography
arterial stiffness
cardioankle vascular index cavi
prognosis
cardiovascular events
title Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)
title_full Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)
title_fullStr Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)
title_full_unstemmed Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)
title_short Contribution of cardio-ankle vascular index to prediction of cardiovascular events in the adult urban population: data from the ESSE-RF study (Tomsk)
title_sort contribution of cardio ankle vascular index to prediction of cardiovascular events in the adult urban population data from the esse rf study tomsk
topic esse-rf
volume sphygmography
arterial stiffness
cardioankle vascular index cavi
prognosis
cardiovascular events
url https://cardiovascular.elpub.ru/jour/article/view/2967
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