Helicobacter pylori and gastric cancer

Introduction: Helicobacter pylori has been linked to the development of chronic atrophic gastritis, intestinal metaplasia, and dysplasia, lesions that can progress to gastric carcinoma. There is research showing that the eradication of this bacterium reduces the risk of histopathological progression...

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Main Authors: Ludmila Martínez Leyva, Teresita de Jesús Montero González, Felipe Neri Piñol Jiménez, Amada Belquis Palomino Besada, Miguel González-Carbajal Pascual, Danay Días Morejón
Format: Article
Language:Spanish
Published: Editorial Ciencias Médicas - ECIMED 2020-10-01
Series:Revista Cubana de Medicina Militar
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Online Access:http://www.revmedmilitar.sld.cu/index.php/mil/article/view/616
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author Ludmila Martínez Leyva
Teresita de Jesús Montero González
Felipe Neri Piñol Jiménez
Amada Belquis Palomino Besada
Miguel González-Carbajal Pascual
Danay Días Morejón
author_facet Ludmila Martínez Leyva
Teresita de Jesús Montero González
Felipe Neri Piñol Jiménez
Amada Belquis Palomino Besada
Miguel González-Carbajal Pascual
Danay Días Morejón
author_sort Ludmila Martínez Leyva
collection DOAJ
description Introduction: Helicobacter pylori has been linked to the development of chronic atrophic gastritis, intestinal metaplasia, and dysplasia, lesions that can progress to gastric carcinoma. There is research showing that the eradication of this bacterium reduces the risk of histopathological progression of preneoplastic lesions, except for intestinal metaplasia and dysplasia. A bibliographic review was made of the articles published in the Pubmed, Scielo, Medline and Cochrane data bases, related to the topic, belonging to authors dedicated to the study of this problem. Objective: To go deepen in the knowledge related to Helicobacter pylori infection and gastric cancer. Development: Adenocarcinoma is the most frequent gastric tumor and Helicobacter pylori is the main etiologic agent. In high-risk populations, gastric adenocarcinoma of the intestinal type is preceded by preneoplastic lesions (atrophy, intestinal metaplasia, and dysplasia) that progresses to invasive cancer. Conclusions: Helicobacter pylori favors gastric carcinogenesis, although there are other risk factors for the development of gastric cancer such as: family history, poor intake of fruits and vegetables, and low socioeconomic level.
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language Spanish
publishDate 2020-10-01
publisher Editorial Ciencias Médicas - ECIMED
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series Revista Cubana de Medicina Militar
spelling doaj-art-fd8ecfba25144b3eba42eb5900cd9a562025-08-20T02:04:40ZspaEditorial Ciencias Médicas - ECIMEDRevista Cubana de Medicina Militar1561-30461561-30462020-10-01494e0200616e0200616304Helicobacter pylori and gastric cancerLudmila Martínez Leyva0Teresita de Jesús Montero González1Felipe Neri Piñol Jiménez2Amada Belquis Palomino Besada3Miguel González-Carbajal Pascual4Danay Días Morejón5HMC Dr. Carlos J. FinlayHMC Dr. Luis Días SotoCNCMAHMC Dr. Carlos J. FinlayHospital Clínico-quirúrgico Joaquín AlbarránHMC Dr. Carlos J. FinlayIntroduction: Helicobacter pylori has been linked to the development of chronic atrophic gastritis, intestinal metaplasia, and dysplasia, lesions that can progress to gastric carcinoma. There is research showing that the eradication of this bacterium reduces the risk of histopathological progression of preneoplastic lesions, except for intestinal metaplasia and dysplasia. A bibliographic review was made of the articles published in the Pubmed, Scielo, Medline and Cochrane data bases, related to the topic, belonging to authors dedicated to the study of this problem. Objective: To go deepen in the knowledge related to Helicobacter pylori infection and gastric cancer. Development: Adenocarcinoma is the most frequent gastric tumor and Helicobacter pylori is the main etiologic agent. In high-risk populations, gastric adenocarcinoma of the intestinal type is preceded by preneoplastic lesions (atrophy, intestinal metaplasia, and dysplasia) that progresses to invasive cancer. Conclusions: Helicobacter pylori favors gastric carcinogenesis, although there are other risk factors for the development of gastric cancer such as: family history, poor intake of fruits and vegetables, and low socioeconomic level.http://www.revmedmilitar.sld.cu/index.php/mil/article/view/616helicobacter pylorigastritis crónica atróficametaplasia intestinaldisplasiacarcinoma gástrico.
spellingShingle Ludmila Martínez Leyva
Teresita de Jesús Montero González
Felipe Neri Piñol Jiménez
Amada Belquis Palomino Besada
Miguel González-Carbajal Pascual
Danay Días Morejón
Helicobacter pylori and gastric cancer
Revista Cubana de Medicina Militar
helicobacter pylori
gastritis crónica atrófica
metaplasia intestinal
displasia
carcinoma gástrico.
title Helicobacter pylori and gastric cancer
title_full Helicobacter pylori and gastric cancer
title_fullStr Helicobacter pylori and gastric cancer
title_full_unstemmed Helicobacter pylori and gastric cancer
title_short Helicobacter pylori and gastric cancer
title_sort helicobacter pylori and gastric cancer
topic helicobacter pylori
gastritis crónica atrófica
metaplasia intestinal
displasia
carcinoma gástrico.
url http://www.revmedmilitar.sld.cu/index.php/mil/article/view/616
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AT teresitadejesusmonterogonzalez helicobacterpyloriandgastriccancer
AT felipeneripinoljimenez helicobacterpyloriandgastriccancer
AT amadabelquispalominobesada helicobacterpyloriandgastriccancer
AT miguelgonzalezcarbajalpascual helicobacterpyloriandgastriccancer
AT danaydiasmorejon helicobacterpyloriandgastriccancer