CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria
Background. CD4 count measures the degree of immunosuppression in HIV-positive patients. It is also used in deciding when to commence therapy, in staging the disease, and in determining treatment failure. Using the CD4 count, this study aimed at determining the percentage of HIV-positives who requir...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | AIDS Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2012/352753 |
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| author | Akinsegun Akinbami Adedoyin Dosunmu Adewumi Adediran Sarah Ajibola Olajumoke Oshinaike Kikelomo Wright Olanrewaju Arogundade |
| author_facet | Akinsegun Akinbami Adedoyin Dosunmu Adewumi Adediran Sarah Ajibola Olajumoke Oshinaike Kikelomo Wright Olanrewaju Arogundade |
| author_sort | Akinsegun Akinbami |
| collection | DOAJ |
| description | Background. CD4 count measures the degree of immunosuppression in HIV-positive patients. It is also used in deciding when to commence therapy, in staging the disease, and in determining treatment failure. Using the CD4 count, this study aimed at determining the percentage of HIV-positives who require antiretroviral therapy at enrollment in an HIV treatment and care centre. Methods. The Baseline CD4 count, age and gender of 4,042 HAART-naïve patients, who registered between December 2006 and June 2010, at Lagos State University Teaching Hospital, Ikeja, were retrospectively studied. Data were analyzed using SPSS version 16.0 (Statistical Package for Social Sciences, Inc., Chicago, Ill). Results. Patients consisted of 2507 (62%) female and 1535 (38%) males. The mean age of males was years and that of females years. Overall, the mean CD4 count was of
cells/mm3. The mean CD4 count of males was
cells/mm3 and that of females cells/mm3. A total of 72.3% males, 64.3% females and 67.4% overall registered patients had CD4 count <350 cells/mm3, while only 15.1% males , 20.3% females, and 18.3% overall registered patients had CD4 count >500 cells/mm3 at registration. Conclusion. Females account for more than half of registered patients in HIV clinic and have a relatively higher CD4 count than males. About three-quarter of HIV positives require antiretroviral therapy at registration. |
| format | Article |
| id | doaj-art-fd8eb2babf34435daefd18fd617172d9 |
| institution | Kabale University |
| issn | 2090-1240 2090-1259 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | AIDS Research and Treatment |
| spelling | doaj-art-fd8eb2babf34435daefd18fd617172d92025-02-03T07:24:58ZengWileyAIDS Research and Treatment2090-12402090-12592012-01-01201210.1155/2012/352753352753CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, NigeriaAkinsegun Akinbami0Adedoyin Dosunmu1Adewumi Adediran2Sarah Ajibola3Olajumoke Oshinaike4Kikelomo Wright5Olanrewaju Arogundade6Department of Haematology and Blood Transfusion, College of Medicine, Lagos State University, Ikeja, PMB 21266, Lagos, NigeriaDepartment of Haematology and Blood Transfusion, College of Medicine, Lagos State University, Ikeja, PMB 21266, Lagos, NigeriaDepartment of Haematology and Blood Transfusion, Faculty of Clinical Sciences, College of Medicine, University of Lagos, PMB 12003, Idiaraba, Lagos, NigeriaDepartment of Haematology and Blood Transfusion, Lagos University Teaching Hospital, PMB 12003, Idiaraba, Lagos, NigeriaDepartment of Medicine, College of Medicine, Lagos State University, Ikeja, PMB 1266, Lagos, NigeriaDepartment of Community Health and Primary Health Care, College of Medicine, Lagos State University, Ikeja, PMB 21266, Lagos, NigeriaDepartment of Haematology and Blood Transfusion, College of Medicine, Lagos State University, Ikeja, PMB 21266, Lagos, NigeriaBackground. CD4 count measures the degree of immunosuppression in HIV-positive patients. It is also used in deciding when to commence therapy, in staging the disease, and in determining treatment failure. Using the CD4 count, this study aimed at determining the percentage of HIV-positives who require antiretroviral therapy at enrollment in an HIV treatment and care centre. Methods. The Baseline CD4 count, age and gender of 4,042 HAART-naïve patients, who registered between December 2006 and June 2010, at Lagos State University Teaching Hospital, Ikeja, were retrospectively studied. Data were analyzed using SPSS version 16.0 (Statistical Package for Social Sciences, Inc., Chicago, Ill). Results. Patients consisted of 2507 (62%) female and 1535 (38%) males. The mean age of males was years and that of females years. Overall, the mean CD4 count was of cells/mm3. The mean CD4 count of males was cells/mm3 and that of females cells/mm3. A total of 72.3% males, 64.3% females and 67.4% overall registered patients had CD4 count <350 cells/mm3, while only 15.1% males , 20.3% females, and 18.3% overall registered patients had CD4 count >500 cells/mm3 at registration. Conclusion. Females account for more than half of registered patients in HIV clinic and have a relatively higher CD4 count than males. About three-quarter of HIV positives require antiretroviral therapy at registration.http://dx.doi.org/10.1155/2012/352753 |
| spellingShingle | Akinsegun Akinbami Adedoyin Dosunmu Adewumi Adediran Sarah Ajibola Olajumoke Oshinaike Kikelomo Wright Olanrewaju Arogundade CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria AIDS Research and Treatment |
| title | CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria |
| title_full | CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria |
| title_fullStr | CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria |
| title_full_unstemmed | CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria |
| title_short | CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria |
| title_sort | cd4 count pattern and demographic distribution of treatment naive hiv patients in lagos nigeria |
| url | http://dx.doi.org/10.1155/2012/352753 |
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