Association of C1QTNF6 gene polymorphism with risk and clinical features of type 1 diabetes in Chinese: implications for ZnT8A and beta-cell function

Association of C1QTNF6 gene polymorphism with risk and clinical features of type 1 diabetes in Chinese: implications for ZnT8A and beta-cell function

IntroductionGenome-wide association study identified C1QTNF6 as a candidate gene for type 1 diabetes (T1D) in Caucasians. We aimed to investigate if rs229541 in C1QTNF6 conferred susceptibility to T1D in Chinese, independent of DR-DQ genotypes and if this gene polymorphism affected the clinical prof...

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Bibliographic Details
Main Authors: Jinhan Liu, Ying Xia, Zhiguo Xie, Xia Li, Gan Huang, Jingyi Hu, Zhiguang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
type 1 diabetes
Genetics
C1QTNF6
Autoimmunity
Beta-cell function
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1551552/full
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